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Cellosaurus LNCaP95 clone E2 (CVCL_A4EC)

[Text version]
Cell line name LNCaP95 clone E2
Accession CVCL_A4EC
Resource Identification Initiative To cite this cell line use: LNCaP95 clone E2 (RRID:CVCL_A4EC)
Comments Population: Caucasian.
Characteristics: Androgen-independent.
Doubling time: 64.1 hours (PubMed=32954481).
Derived from site: Metastatic; Left supraclavicular lymph node; UBERON=UBERON_8480056.
Sequence variations
  • Mutation; HGNC; HGNC:644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
  • Mutation; HGNC; HGNC:7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_ZC87 (LNCaP-95)
Sex of cell Male
Age at sampling 50Y
Category Cancer cell line
Publications

PubMed=32954481; DOI=10.1007/s13577-020-00435-6; PMCID=PMC8693726
Leung J.K., Tam T., Wang J., Sadar M.D.
Isolation and characterization of castration-resistant prostate cancer LNCaP95 clones.
Hum. Cell 34:211-218(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A4EC
Encyclopedic resources Wikidata; Q105509935
Entry history
Entry creation12-Jan-2021
Last entry update19-Dec-2024
Version number7