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Cellosaurus TF-1-Luc2 (CVCL_A4BP)

[Text version]
Cell line name TF-1-Luc2
Accession CVCL_A4BP
Resource Identification Initiative To cite this cell line use: TF-1-Luc2 (RRID:CVCL_A4BP)
Comments Population: Japanese.
Characteristics: Stably expresses firefly luciferase under the control of the human EF1a promoter (ATCC=CRL-2003-LUC2).
Doubling time: ~19 hours (ATCC=CRL-2003-LUC2).
Transfected with: UniProtKB; P08659; Firefly luciferase (with optimized codon usage for mammalian expression).
Transfected with: UniProtKB; P33967; B.cereus Bsr.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Gene fusion; HGNC; 15868; ABHD12 + HGNC; 1537; CBFA2T3; Name(s)=CBFA2T3-ABHD12 (from parent cell line).
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Pro (c.182A>C); ClinVar=VCV000280409; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Ile251Thrfs*94 (c.752delT); ClinVar=VCV001759367; Zygosity=Unspecified (from parent cell line).
Disease Erythroleukemia (NCIt: C7152)
Acute erythroid leukemia (ORDO: Orphanet_318)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0559 (TF-1)
Sex of cell Male
Age at sampling 35Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-2003-LUC2

Markers:
AmelogeninX,Y
CSF1PO13
D5S81813
D7S82012
D13S3178,9
D16S5399,12
TH017,9
TPOX8
vWA15,17

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Cross-references
Cell line collections (Providers) ATCC; CRL-2003-LUC2
Cell line databases/resources cancercelllines; CVCL_A4BP
Encyclopedic resources Wikidata; Q105511173
Entry history
Entry creation12-Jan-2021
Last entry update02-May-2024
Version number6