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Cellosaurus Agarabi CHO (CVCL_A4AR)

[Text version]
Cell line name Agarabi CHO
Accession CVCL_A4AR
Resource Identification Initiative To cite this cell line use: Agarabi CHO (RRID:CVCL_A4AR)
Comments Characteristics: Parent cell line was stably transfected with a two-vector system expressing a model mouse-human chimeric IgG1 antibody.
Doubling time: 22-28 hours (ATCC=CRL-3440).
Selected for resistance to: ChEBI; CHEBI_44185; Methotrexate (MTX).
Transformant: NCIt; C129640; Cobalt-60 gamma radiation.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations
  • Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Homozygous (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_7180 (CHO-DG44)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=29086492; DOI=10.1002/btpr.2575; PMCID=PMC5821576
Velugula-Yellela S.R., Williams A., Trunfio N., Hsu C.-J., Chavez B., Yoon S., Agarabi C.
Impact of media and antifoam selection on monoclonal antibody production and quality using a high throughput micro-bioreactor system.
Biotechnol. Prog. 34:262-270(2018)

Cross-references
Cell line collections (Providers) ATCC; CRL-3440
Encyclopedic resources Wikidata; Q105506379
Entry history
Entry creation12-Jan-2021
Last entry update19-Dec-2024
Version number6