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Cellosaurus MZ-MEL-5 (CVCL_A468)

[Text version]
Cell line name MZ-MEL-5
Synonyms MZ-Mel-5; Mz-Mel-5; MZ MEL 5; MZ5-MEL
Accession CVCL_A468
Resource Identification Initiative To cite this cell line use: MZ-MEL-5 (RRID:CVCL_A468)
Sequence variations
HLA typing Source: PubMed=15592718
Class I
HLA-AA*32:01,26:01
HLA-BB*07:02,57:02
HLA-CC*07:02,06:02
Class II
HLA-DPDPB1*04:01,04:02
HLA-DQDQB1*06:02,05:01
HLA-DRDRB1*15:01,01:01
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): ESTDAB=ESTDAB-056

Markers:
AmelogeninX,Y
CSF1PO12
D3S135816
D5S81811
D7S8208,13
D13S31711,12
FGA21,25
TH017,9.3
TPOX8
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=15592718; DOI=10.1007/s00262-004-0561-5; PMCID=PMC11032966
Rodriguez T., Mendez R., Roberts C.H., Ruiz-Cabello Osuna F., Dodi I.A., Lopez-Nevot M.A., Paco L., Maleno I., Marsh S.G.E., Pawelec G., Garrido F.
High frequency of homozygosity of the HLA region in melanoma cell lines reveals a pattern compatible with extensive loss of heterozygosity.
Cancer Immunol. Immunother. 54:141-148(2005)

PubMed=23851445; DOI=10.1158/1541-7786.MCR-13-0006
Dahl C., Christensen C., Jonsson G., Lorentzen A., Skjodt M.L., Borg A., Pawelec G., Guldberg P.
Mutual exclusivity analysis of genetic and epigenetic drivers in melanoma identifies a link between p14 ARF and RARbeta signaling.
Mol. Cancer Res. 11:1166-1178(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A468
ESTDAB; ESTDAB-056
Encyclopedic resources Wikidata; Q54907226
Polymorphism and mutation databases Cosmic; 972269
Cosmic; 2163797
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number18