Cellosaurus YK6-CD40Lg-IL21 (CVCL_A2XK)
| Cell line name | YK6-CD40Lg-IL21 |
|---|---|
| Accession | CVCL_A2XK |
| Resource Identification Initiative | To cite this cell line use: YK6-CD40Lg-IL21 (RRID:CVCL_A2XK) |
| Comments | Population: Korean. Characteristics: Used as a feeder line to co-culture with human B cells. Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:11935; CD40LG. Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:1773; CDK4 (Note=With p.Arg24Cys). Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:6005; IL21. Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:11730; TERT. Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:88346; Cd8a. Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:98834; Trp53 (Note=With p.Leu14_Lys302del = p53DD). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR). Miscellaneous: Sex assignment derived from omics analysis from personal communication of Hodson, Daniel James. Derived from site: In situ; Oral cavity, tonsil; UBERON=UBERON_0002372. Cell type: Follicular dendritic cell; CL=CL_0000442. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_A2XJ (YK6) |
| Sex of cell | Male |
| Age at sampling | Children |
| Category | Telomerase immortalized cell line |
| Publications | PubMed=31586074; DOI=10.1038/s41467-019-12494-x; PMCID=PMC6778131 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q105511836 |
| Entry history | |
| Entry creation | 12-Jan-2021 |
| Last entry update | 19-Dec-2024 |
| Version number | 9 |