Cellosaurus logo
expasy logo

Cellosaurus YK6 (CVCL_A2XJ)

[Text version]
Cell line name YK6
Accession CVCL_A2XJ
Resource Identification Initiative To cite this cell line use: YK6 (RRID:CVCL_A2XJ)
Comments Population: Korean.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:1773; CDK4 (Note=With p.Arg24Cys).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:98834; Trp53 (Note=With p.Leu14_Lys302del = p53DD).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Miscellaneous: Sex assignment derived from omics analysis from personal communication of Hodson, Daniel James.
Derived from site: In situ; Oral cavity, tonsil; UBERON=UBERON_0002372.
Cell type: Follicular dendritic cell; CL=CL_0000442.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_A2XK (YK6-CD40Lg-IL21)
Sex of cell Male
Age at sampling Children
Category Telomerase immortalized cell line
Publications

PubMed=31586074; DOI=10.1038/s41467-019-12494-x; PMCID=PMC6778131
Caeser R., Di Re M., Krupka J.A., Gao J., Lara-Chica M., Dias J.M.L., Cooke S.L., Fenner R., Usheva Z., Runge H.F.P., Beer P.A., Eldaly H., Pak H.-K., Park C.-S., Vassiliou G.S., Huntly B.J.P., Mupo A., Bashford-Rogers R.J.M., Hodson D.J.
Genetic modification of primary human B cells to model high-grade lymphoma.
Nat. Commun. 10:4543.1-4543.16(2019)

Cross-references
Encyclopedic resources Wikidata; Q105511834
Entry history
Entry creation12-Jan-2021
Last entry update19-Dec-2024
Version number9