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Cellosaurus V79-hCYP1A2-hNAT1 (CVCL_A2GZ)

[Text version]
Cell line name V79-hCYP1A2-hNAT1
Synonyms V79-CYP1A2-NAT1
Accession CVCL_A2GZ
Resource Identification Initiative To cite this cell line use: V79-hCYP1A2-hNAT1 (RRID:CVCL_A2GZ)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:2596; CYP1A2.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:7645; NAT1.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Fibroblast of lung; CL=CL_0002553.
Sequence variations
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_4V39 (V79-hCYP1A2)
Sex of cell Male
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=14729582; DOI=10.1093/carcin/bgh077
Glatt H.-R., Pabel U., Meinl W., Frederiksen H., Frandsen H., Muckel E.
Bioactivation of the heterocyclic aromatic amine 2-amino-3-methyl-9H-pyrido [2,3-b]indole (MeAalphaC) in recombinant test systems expressing human xenobiotic-metabolizing enzymes.
Carcinogenesis 25:801-807(2004)

Cross-references
Encyclopedic resources Wikidata; Q105511669
Entry history
Entry creation12-Jan-2021
Last entry update19-Dec-2024
Version number7