Cellosaurus cell line HOSM-2 (CVCL

Cellosaurus HOSM-2 (CVCL_A2BJ)

Cross-references
Cell line name	HOSM-2
Synonyms	Human OsteoSarcoma from Mandible-2
Accession	CVCL_A2BJ
Resource Identification Initiative	To cite this cell line use: HOSM-2 (RRID:CVCL_A2BJ)
Comments	Population: Japanese. Doubling time: 74.8 hours (CelloPub=CLPUB00596); 70.6 hours (PubMed=15172645). Karyotypic information: Has lost chromosome Y. Derived from site: In situ; Bone, jaw, mandible; UBERON=UBERON_0001684.
Sequence variations	Mutation; HGNC; 11998; TP53; Simple; p.Arg306Ter (c.916C>T); ClinVar=VCV000142144; Zygosity=Unspecified (PubMed=15172645).
Disease	Osteosarcoma (NCIt: C9145) Osteosarcoma (ORDO: Orphanet_668)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_A2BI ! HOSM-1 CVCL_A2BK ! HOSMN-1C
Sex of cell	Male
Age at sampling	40Y
Category	Cancer cell line
Publications	CLPUB00596 Tagawa T., Nomura J., Kihira H., Murata M. A new established osteosarcoma cell line from human mandible. Mie Med. J. 39:279-286(1989) PubMed=15172645; DOI=10.1016/j.oraloncology.2004.01.015 Narita M., Nomura J., Nakase M., Inui M., Murata T., Hamaguchi Y., Tagawa T. Characterization of the human mandibular osteoblastic osteosarcoma cell line HOSM-2 after long-term culture. Oral Oncol. 40:742-750(2004) PubMed=19878029; DOI=10.1089/pho.2008.2329 Yanase S., Nomura J., Matsumura Y., Watanabe Y., Tagawa T. Synergistic increase in osteosarcoma cell sensitivity to photodynamic therapy with aminolevulinic acid hexyl ester in the presence of hyperthermia. Photomed. Laser Surg. 27:791-797(2009)
Cell line databases/resources	cancercelllines; CVCL_A2BJ
Encyclopedic resources	Wikidata; Q105507713
Polymorphism and mutation databases	IARC_TP53; 20215
Entry history
Entry creation	12-Jan-2021
Last entry update	05-Oct-2023
Version number	5