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Cellosaurus ACC-LC-319/bone2 (CVCL_A1GQ)

[Text version]
Cell line name ACC-LC-319/bone2
Accession CVCL_A1GQ
Resource Identification Initiative To cite this cell line use: ACC-LC-319/bone2 (RRID:CVCL_A1GQ)
Comments Population: Japanese.
Characteristics: Highly metastatic to bone. Obtained after 2 cycles of intravenous injection of parental cells into NK cell-depleted SCID mice and harvesting of the bone metastases.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000045116; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro71fs (c.211delC); Zygosity=Unspecified (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7012 (ACC-LC-319)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=19806789; DOI=10.3727/096504009789745511
Otsuka S., Hanibuchi M., Ikuta K., Yano S., Goto H., Ogino H., Yamada T., Kakiuchi S., Nishioka Y., Takahashi T., Sone S.
A bone metastasis model with osteolytic and osteoblastic properties of human lung cancer ACC-LC-319/bone2 in natural killer cell-depleted severe combined immunodeficient mice.
Oncol. Res. 17:581-591(2009)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A1GQ
Encyclopedic resources Wikidata; Q102113500
Entry history
Entry creation29-Oct-2020
Last entry update19-Dec-2024
Version number7