ID   ACC-LC-319/bone2
AC   CVCL_A1GQ
DR   cancercelllines; CVCL_A1GQ
DR   Wikidata; Q102113500
RX   PubMed=19806789;
CC   Population: Japanese.
CC   Characteristics: Highly metastatic to bone. Obtained after 2 cycles of intravenous injection of parental cells into NK cell-depleted SCID mice and harvesting of the bone metastases.
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000045116; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro71fs (c.211delC); Zygosity=Unspecified (from parent cell line).
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_7012 ! ACC-LC-319
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 29-10-20; Last updated: 19-12-24; Version: 7
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RX   PubMed=19806789; DOI=10.3727/096504009789745511;
RA   Otsuka S., Hanibuchi M., Ikuta K., Yano S., Goto H., Ogino H.,
RA   Yamada T., Kakiuchi S., Nishioka Y., Takahashi T., Sone S.;
RT   "A bone metastasis model with osteolytic and osteoblastic properties
RT   of human lung cancer ACC-LC-319/bone2 in natural killer cell-depleted
RT   severe combined immunodeficient mice.";
RL   Oncol. Res. 17:581-591(2009).
//