Cellosaurus cell line Ma-Mel-43 (CVCL

Cellosaurus Ma-Mel-43 (CVCL_A179)

Cross-references
Cell line name	Ma-Mel-43
Accession	CVCL_A179
Resource Identification Initiative	To cite this cell line use: Ma-Mel-43 (RRID:CVCL_A179)
Comments	Derived from site: Metastatic; Hypodermis; UBERON=UBERON_0002072. Derived from site: Metastatic; Skin; UBERON=UBERON_0002097.
Sequence variations	Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000013900; Zygosity=Unspecified (PubMed=17311103; PubMed=23348503).
Disease	Melanoma (NCIt: C3224)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	48Y
Category	Cancer cell line
Publications	PubMed=15760917; DOI=10.1093/carcin/bgi066 Bloethner S., Chen B.-W., Hemminki K., Mueller-Berghaus J., Ugurel S., Schadendorf D., Kumar R. Effect of common B-RAF and N-RAS mutations on global gene expression in melanoma cell lines. Carcinogenesis 26:1224-1232(2005) PubMed=17311103; DOI=10.1371/journal.pone.0000236; PMCID=PMC1794595 Ugurel S., Thirumaran R.K., Bloethner S., Gast A., Sucker A., Mueller-Berghaus J., Rittgen W., Hemminki K., Becker J.C., Kumar R., Schadendorf D. B-RAF and N-RAS mutations are preserved during short time in vitro propagation and differentially impact prognosis. PLoS ONE 2:E236-E236(2007) PubMed=23348503; DOI=10.1126/science.1230062 Horn S., Figl A., Rachakonda P.S., Fischer C., Sucker A., Gast A., Kadel S., Moll I., Nagore E., Hemminki K., Schadendorf D., Kumar R. TERT promoter mutations in familial and sporadic melanoma. Science 339:959-961(2013)
Cell line databases/resources	cancercelllines; CVCL_A179
Encyclopedic resources	Wikidata; Q54903800
Polymorphism and mutation databases	Cosmic; 906466 Cosmic; 2686408
Entry history
Entry creation	06-Jun-2012
Last entry update	19-Dec-2024
Version number	15