ID   Ma-Mel-43
AC   CVCL_A179
DR   cancercelllines; CVCL_A179
DR   Cosmic; 906466
DR   Cosmic; 2686408
DR   Wikidata; Q54903800
RX   PubMed=15760917;
RX   PubMed=17311103;
RX   PubMed=23348503;
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000013900; Zygosity=Unspecified (PubMed=17311103; PubMed=23348503).
CC   Derived from site: Metastatic; Hypodermis; UBERON=UBERON_0002072.
CC   Derived from site: Metastatic; Skin; UBERON=UBERON_0002097.
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   48Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 15
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RX   PubMed=15760917; DOI=10.1093/carcin/bgi066;
RA   Bloethner S., Chen B.-W., Hemminki K., Mueller-Berghaus J., Ugurel S.,
RA   Schadendorf D., Kumar R.;
RT   "Effect of common B-RAF and N-RAS mutations on global gene expression
RT   in melanoma cell lines.";
RL   Carcinogenesis 26:1224-1232(2005).
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RX   PubMed=17311103; DOI=10.1371/journal.pone.0000236; PMCID=PMC1794595;
RA   Ugurel S., Thirumaran R.K., Bloethner S., Gast A., Sucker A.,
RA   Mueller-Berghaus J., Rittgen W., Hemminki K., Becker J.C., Kumar R.,
RA   Schadendorf D.;
RT   "B-RAF and N-RAS mutations are preserved during short time in vitro
RT   propagation and differentially impact prognosis.";
RL   PLoS ONE 2:E236-E236(2007).
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RX   PubMed=23348503; DOI=10.1126/science.1230062;
RA   Horn S., Figl A., Rachakonda P.S., Fischer C., Sucker A., Gast A.,
RA   Kadel S., Moll I., Nagore E., Hemminki K., Schadendorf D., Kumar R.;
RT   "TERT promoter mutations in familial and sporadic melanoma.";
RL   Science 339:959-961(2013).
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