Cellosaurus cell line Ma-Mel-37b (CVCL

Cellosaurus Ma-Mel-37b (CVCL_A173)

[Text version]

Cell line name

Ma-Mel-37b

Accession

CVCL_A173

Resource Identification Initiative

To cite this cell line use: Ma-Mel-37b (RRID:CVCL_A173)

Comments

Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.

Sequence variations

Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Unspecified (PubMed=17311103; PubMed=23348503).
Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).

Disease

Cutaneous nodular melanoma (NCIt: C4225)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Originate from same individual

CVCL_A172 ! Ma-Mel-37a

Sex of cell

Female

Age at sampling

59Y

Category

Cancer cell line

STR profile

Source(s): ESTDAB=ESTDAB-211

Markers:

Amelogenin	X
CSF1PO	8,10
D3S1358	14,16
D5S818	11,13
D7S820	11,12
D13S317	9,11
FGA	21,25
TH01	6,9
TPOX	8
vWA	14,17

Publications

PubMed=17311103; DOI=10.1371/journal.pone.0000236; PMCID=PMC1794595
Ugurel S., Thirumaran R.K., Bloethner S., Gast A., Sucker A., Mueller-Berghaus J., Rittgen W., Hemminki K., Becker J.C., Kumar R., Schadendorf D.
B-RAF and N-RAS mutations are preserved during short time in vitro propagation and differentially impact prognosis.
PLoS ONE 2:E236-E236(2007)

PubMed=23348503; DOI=10.1126/science.1230062
Horn S., Figl A., Rachakonda P.S., Fischer C., Sucker A., Gast A., Kadel S., Moll I., Nagore E., Hemminki K., Schadendorf D., Kumar R.
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_A173
ESTDAB; ESTDAB-211

Anatomy/cell type resources

BTO; BTO_0005343

Encyclopedic resources

Wikidata; Q54903791

Polymorphism and mutation databases

Cosmic; 1846618
Cosmic; 2686401

Entry history

Entry creation

06-Jun-2012

Last entry update

19-Dec-2024

Version number