Cellosaurus logo
expasy logo

Cellosaurus Ma-Mel-37a (CVCL_A172)

[Text version]
Cell line name Ma-Mel-37a
Synonyms MaMel37a
Accession CVCL_A172
Resource Identification Initiative To cite this cell line use: Ma-Mel-37a (RRID:CVCL_A172)
Comments Omics: SNP array analysis.
Sequence variations
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Gln50Ter (c.148C>T); ClinVar=VCV000220711; Zygosity=Unspecified (PubMed=20544847).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Unspecified (PubMed=23348503).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
Disease Cutaneous nodular melanoma (NCIt: C4225)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A173 ! Ma-Mel-37b
Sex of cell Female
Age at sampling 59Y
Category Cancer cell line
Publications

PubMed=20544847; DOI=10.1002/gcc.20785
Gast A., Scherer D., Chen B.-W., Bloethner S., Melchert S., Sucker A., Hemminki K., Schadendorf D., Kumar R.
Somatic alterations in the melanoma genome: a high-resolution array-based comparative genomic hybridization study.
Genes Chromosomes Cancer 49:733-745(2010)

PubMed=23348503; DOI=10.1126/science.1230062
Horn S., Figl A., Rachakonda P.S., Fischer C., Sucker A., Gast A., Kadel S., Moll I., Nagore E., Hemminki K., Schadendorf D., Kumar R.
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A172
IGRhCellID; MaMel37a
Encyclopedic resources Wikidata; Q54903790
Gene expression databases GEO; GSM437004
Polymorphism and mutation databases Cosmic; 1467753
Cosmic; 1846617
Cosmic; 2686400
Progenetix; CVCL_A172
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number17