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Cellosaurus HGrC1-YAP (CVCL_A0TX)

[Text version]
Cell line name HGrC1-YAP
Accession CVCL_A0TX
Resource Identification Initiative To cite this cell line use: HGrC1-YAP (RRID:CVCL_A0TX)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:16262; YAP1.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Ovary, ovarian follicle, granulosa cell layer; UBERON=UBERON_0005170.
Cell type: Granulosa cell; CL=CL_0000501.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_KB28 (HGrC1)
Sex of cell Female
Age at sampling 35Y
Category Transformed cell line
Publications

PubMed=34888112; DOI=10.1016/j.scib.2020.03.040; PMCID=PMC8654108
Lv X.-M., He C.-B., Huang C., Hua G.-H., Chen X.-C., Timm B.K., Maclin V.M., Haggerty A.A., Aust S.K., Golden D.M., Dave B.J., Tseng Y.-A., Chen L., Wang H.-B., Chen P.-C., Klinkebiel D.L., Karpf A.R., Dong J.-X., Drapkin R.I., Rueda B.R., Davis J.S., Wang C.
Reprogramming of ovarian granulosa cells by YAP1 leads to development of high-grade cancer with mesenchymal lineage and serous features.
Sci. Bull. 65:1281-1296(2020)

Cross-references
Encyclopedic resources Wikidata; Q108820465
Entry history
Entry creation23-Sep-2021
Last entry update19-Dec-2024
Version number8