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Cellosaurus MDCKII-MRP2/UGT1A1 (CVCL_9U72)

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Cell line name MDCKII-MRP2/UGT1A1
Synonyms MDCKII-UGT1A1/MRP2
Accession CVCL_9U72
Resource Identification Initiative To cite this cell line use: MDCKII-MRP2/UGT1A1 (RRID:CVCL_9U72)
Comments Genetic integration: Method=Transfection; Gene=HGNC; 53; ABCC2.
Genetic integration: Method=Transfection; Gene=HGNC; 12530; UGT1A1.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Cocker Spaniel; VBO=VBO_0200372.
Hierarchy Parent: CVCL_X022 (MDCK-MRP2)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=26833852; DOI=10.1002/mnfr.201500321; PMCID=PMC5358013
Wang M.-F., Yang G.-Y., He Y., Xu B.-B., Zeng M., Ge S.-F., Yin T.-J., Gao S., Hu M.
Establishment and use of new MDCK II cells overexpressing both UGT1A1 and MRP2 to characterize flavonoid metabolism via the glucuronidation pathway.
Mol. Nutr. Food Res. 60:1967-1983(2016)

Cross-references
Encyclopedic resources Wikidata; Q54904807
Entry history
Entry creation23-Feb-2016
Last entry update10-Sep-2024
Version number9