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Cellosaurus NHEK/SV3 (CVCL_9Q50)

[Text version]
Cell line name NHEK/SV3
Accession CVCL_9Q50
Resource Identification Initiative To cite this cell line use: NHEK/SV3 (RRID:CVCL_9Q50)
Comments Senescence: SV40-transformed but with a finite life span (maximum PDL is 30) (Evercyte=CLT-011-0026).
Doubling time: ~48 hours (Evercyte=CLT-011-0026).
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Abdomen, skin, epidermis; UBERON=UBERON_0001416+UBERON_0001003.
Cell type: Keratinocyte; CL=CL_0000312.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_9Q51 (NHEK/SVTERT3-5)
Sex of cell Female
Age at sampling Age unspecified
Category Finite cell line
Web pages Provider; Evercyte; CLT-011-0026; https://web.archive.org/web/20150302212441/http://www.evercyte.com:80/medizin/cell-lines/immortalized-human-somatic-cells/nhek-sv3.html
Publications

PubMed=28776197; DOI=10.1007/s00204-017-2034-6; PMCID=PMC5773649
Weinmuellner R., Kryeziu K., Zbiral B., Tav K., Schoenhacker-Alte B., Groza D., Wimmer L.R., Schosserer M., Nagelreiter F., Rosinger S., Mildner M., Tschachler E., Grusch M., Grillari J., Heffeter P.
Long-term exposure of immortalized keratinocytes to arsenic induces EMT, impairs differentiation in organotypic skin models and mimics aspects of human skin derangements.
Arch. Toxicol. 92:181-194(2018)

Cross-references
Cell line collections (Providers) Evercyte; CLT-011-0026 - Discontinued
Encyclopedic resources Wikidata; Q54930513
Entry history
Entry creation23-Feb-2016
Last entry update10-Apr-2025
Version number13