Cellosaurus cell line STA-ET-7.2 (CVCL

Cellosaurus STA-ET-7.2 (CVCL_9693)

Cross-references
Cell line name	STA-ET-7.2
Synonyms	STA-ET-7_2; St. Anna Kinderspital-Ewing Tumor-7.2
Accession	CVCL_9693
Resource Identification Initiative	To cite this cell line use: STA-ET-7.2 (RRID:CVCL_9693)
Comments	From: Children's Cancer Research Institute; Vienna; Austria. Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273Cys (c.817C>T); ClinVar=VCV000043594; Zygosity=Unspecified (PubMed=8378080).
Disease	Ewing sarcoma (NCIt: C4817) Ewing sarcoma (ORDO: Orphanet_319)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_9692 ! STA-ET-7.1 CVCL_9694 ! STA-ET-7.3
Category	Cancer cell line
Publications	PubMed=8378080 Kovar H., Auinger A., Jug G., Aryee D.N.T., Zoubek A., Salzer-Kuntschik M., Gadner H. Narrow spectrum of infrequent p53 mutations and absence of MDM2 amplification in Ewing tumours. Oncogene 8:2683-2690(1993) PubMed=9393981; DOI=10.1038/sj.onc.1201397 Kovar H., Jug G., Aryee D.N.T., Zoubek A., Ambros P.F., Gruber B., Windhager R., Gadner H. Among genes involved in the RB dependent cell cycle regulatory cascade, the p16 tumor suppressor gene is frequently lost in the Ewing family of tumors. Oncogene 15:2225-2232(1997) PubMed=11507040 Kovar H., Jug G., Hattinger C.M., Spahn L., Aryee D.N.T., Ambros P.F., Zoubek A., Gadner H. The EWS protein is dispensable for Ewing tumor growth. Cancer Res. 61:5992-5997(2001)
Cell line databases/resources	cancercelllines; CVCL_9693
Encyclopedic resources	Wikidata; Q54955778
Polymorphism and mutation databases	Cosmic; 1388899 IARC_TP53; 23648
Entry history
Entry creation	06-Jun-2012
Last entry update	19-Dec-2024
Version number	13