ID   STA-ET-7.2
AC   CVCL_9693
SY   STA-ET-7_2; St. Anna Kinderspital-Ewing Tumor-7.2
DR   cancercelllines; CVCL_9693
DR   Cosmic; 1388899
DR   IARC_TP53; 23648
DR   Wikidata; Q54955778
RX   PubMed=8378080;
RX   PubMed=9393981;
RX   PubMed=11507040;
CC   From: Children's Cancer Research Institute; Vienna; Austria.
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273Cys (c.817C>T); ClinVar=VCV000043594; Zygosity=Unspecified (PubMed=8378080).
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C4817; Ewing sarcoma
DI   ORDO; Orphanet_319; Ewing sarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_9692 ! STA-ET-7.1
OI   CVCL_9694 ! STA-ET-7.3
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 13
//
RX   PubMed=8378080;
RA   Kovar H., Auinger A., Jug G., Aryee D.N.T., Zoubek A.,
RA   Salzer-Kuntschik M., Gadner H.;
RT   "Narrow spectrum of infrequent p53 mutations and absence of MDM2
RT   amplification in Ewing tumours.";
RL   Oncogene 8:2683-2690(1993).
//
RX   PubMed=9393981; DOI=10.1038/sj.onc.1201397;
RA   Kovar H., Jug G., Aryee D.N.T., Zoubek A., Ambros P.F., Gruber B.,
RA   Windhager R., Gadner H.;
RT   "Among genes involved in the RB dependent cell cycle regulatory
RT   cascade, the p16 tumor suppressor gene is frequently lost in the Ewing
RT   family of tumors.";
RL   Oncogene 15:2225-2232(1997).
//
RX   PubMed=11507040;
RA   Kovar H., Jug G., Hattinger C.M., Spahn L., Aryee D.N.T., Ambros P.F.,
RA   Zoubek A., Gadner H.;
RT   "The EWS protein is dispensable for Ewing tumor growth.";
RL   Cancer Res. 61:5992-5997(2001).
//