| Cell line name |
3051/80 |
|---|
| Synonyms |
St 3051; St3051 |
|---|
| Accession |
CVCL_9558 |
|---|
| Resource Identification Initiative |
To cite this cell line use: 3051/80 (RRID:CVCL_9558) |
|---|
| Comments |
Problematic cell line: Contaminated. Shown to be a HT-29 derivative (PubMed=10508494; PubMed=20143388). Originally thought to originate from a 66 year old male patient with a gastric carcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00109.
Population: Caucasian.
Derived from site: In situ; Colon; UBERON=UBERON_0001155. |
|---|
| Sequence variations |
- Mutation; HGNC; HGNC:583; APC; Simple; p.Glu853Ter (c.2557G>T); ClinVar=VCV001071632; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Asnfs*3 (c.4666dupA) (c.4666_4667insA); ClinVar=VCV000428112; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Pro449Thr (c.1345C>A); ClinVar=VCV001333250; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Gln311Ter (c.931C>T); ClinVar=VCV000230663; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
|
|---|
| Disease |
Colon adenocarcinoma (NCIt: C4349) |
|---|
| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
|---|
| Hierarchy |
Parent: CVCL_0320 (HT-29) |
|---|
| Sex of cell |
Female |
|---|
| Age at sampling |
44Y |
|---|
| Category |
Cancer cell line |
|---|
| Web pages |
https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx |
|---|
| Publications | PubMed=8100658; DOI=10.1007/BF02899281
Vollmers H.P., Stulle K., Dammrich J., Pfaff M., Papadopoulos T., Betz C., Saal K., Muller-Hermelink H.-K.
Characterization of four new gastric cancer cell lines.
Virchows Arch. B. Cell. Pathol. Incl. Mol. Pathol. 63:335-343(1993) PubMed=10508494; DOI=10.1002/(SICI)1097-0215(19991112)83:4<555::AID-IJC19>3.0.CO;2-2
MacLeod R.A.F., Dirks W.G., Matsuo Y., Kaufmann M., Milch H., Drexler H.G.
Widespread intraspecies cross-contamination of human tumor cell lines arising at source.
Int. J. Cancer 83:555-563(1999) PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010) |
|---|
| Cross-references |
|---|
| Cell line databases/resources |
cancercelllines; CVCL_9558
|
|---|
| Biological sample resources |
BioSample; SAMN03151785
|
|---|
| Encyclopedic resources |
Wikidata; Q54584686
|
|---|
| Entry history |
|---|
| Entry creation | 06-Jun-2012 |
|---|
| Last entry update | 19-Dec-2024 |
|---|
| Version number | 29 |
|---|
