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Cellosaurus OUMS-21 [1993] (CVCL_9131)

[Text version]
Cell line name OUMS-21 [1993]
Synonyms Okayama University Medical School-21
Accession CVCL_9131
Resource Identification Initiative To cite this cell line use: OUMS-21 [1993] (RRID:CVCL_9131)
Comments Population: Japanese.
Senescence: SV40-transformed but with a finite life span.
Doubling time: 29.4 hours (PubMed=7683277).
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSV3-neo).
Caution: Two cell lines named OUMS-21 have been created at Okayama University Medical School, one in 1972 from the peripheral blood of a normal adult donor (Cellosaurus=CVCL_A7SC) and one in 1993 from the SV40-transformed liver of a fetus (Cellosaurus=CVCL_9131).
Derived from site: In situ; Fetal liver; UBERON=UBERON_0002107.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_M266 (MMNK-1)
Originate from same individual CVCL_9132 ! OUMS-22 [1993]
Sex of cell Sex unspecified
Age at sampling 18FW
Category Finite cell line
Publications

DOI=10.1007/978-1-4612-0411-4_32
Namba M., Kano Y., Bai L.-Y., Mihara K., Miyazaki M.
Establishment and characterization of SV40 t-antigen immortalized human liver cells.
(In book chapter) Neoplastic transformation in human cell system. Mechanism of carcinogenesis; Rhim J.S., Dritschilo A. (eds.); pp.323-332; Humana Press; New York; USA (1990)

PubMed=7683277; DOI=10.1006/excr.1993.1116
Miyazaki M., Mihara K., Bai L.-Y., Kano Y., Tsuboi S., Endo A., Seshimo K., Yoshioka T., Namba M.
Immortalization of epithelial-like cells from human liver tissue with SV40 T-antigen gene.
Exp. Cell Res. 206:27-35(1993)

PubMed=14966424; DOI=10.1097/01.TP.0000110292.73873.25
Maruyama M., Kobayashi N., Westerman K.A., Sakaguchi M., Allain J.-E., Totsugawa T., Okitsu T., Fukazawa T., Weber A., Stolz D.B., Leboulch P., Tanaka N.
Establishment of a highly differentiated immortalized human cholangiocyte cell line with SV40T and hTERT.
Transplantation 77:446-451(2004)

Cross-references
Encyclopedic resources Wikidata; Q54936766
Entry history
Entry creation06-Jun-2012
Last entry update10-Sep-2024
Version number21