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Cellosaurus A818-7 (CVCL_8777)

[Text version]
Cell line name A818-7
Synonyms A-818-7; A 818-7; 818-7
Accession CVCL_8777
Secondary accession CVCL_8605
Resource Identification Initiative To cite this cell line use: A818-7 (RRID:CVCL_8777)
Comments Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Arg (c.34G>C); ClinVar=VCV000012579; Zygosity=Unspecified (PubMed=8426738).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3890 (A818)
Sex of cell Female
Age at sampling 75Y
Category Cancer cell line
Publications

PubMed=1906154
Kalthoff H., Roeder C., Humburg I., Thiele H.-G., Greten H., Schmiegel W.H.
Modulation of platelet-derived growth factor A- and B-chain/c-sis mRNA by tumor necrosis factor and other agents in adenocarcinoma cells.
Oncogene 6:1015-1021(1991)

PubMed=8105469; DOI=10.1073/pnas.90.19.8972; PMCID=PMC47483
Kalthoff H., Roeder C., Gieseking J., Humburg I., Schmiegel W.H.
Inverse regulation of human ERBB2 and epidermal growth factor receptors by tumor necrosis factor alpha.
Proc. Natl. Acad. Sci. U.S.A. 90:8972-8976(1993)

PubMed=8426738
Kalthoff H., Schmiegel W.H., Roeder C., Kasche D., Schmidt A., Lauer G., Thiele H.-G., Honold G., Pantel K., Riethmuller G., Scherer E., Maurer J., Maacke H., Deppert W.
p53 and K-RAS alterations in pancreatic epithelial cell lesions.
Oncogene 8:289-298(1993)

PubMed=8430098; DOI=10.1073/pnas.90.3.863; PMCID=PMC45770
Schmiegel W.H., Roeder C., Schmielau J., Rodeck U., Kalthoff H.
Tumor necrosis factor alpha induces the expression of transforming growth factor alpha and the epidermal growth factor receptor in human pancreatic cancer cells.
Proc. Natl. Acad. Sci. U.S.A. 90:863-867(1993)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8777
Encyclopedic resources Wikidata; Q54607229
Polymorphism and mutation databases Cosmic; 736268
Cosmic; 933526
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number16