Cellosaurus logo
expasy logo

Cellosaurus HONE-1 (CVCL_8706)

[Text version]
Cell line name HONE-1
Synonyms Hone-1; HONE1; Hone1
Accession CVCL_8706
Resource Identification Initiative To cite this cell line use: HONE-1 (RRID:CVCL_8706)
Comments Problematic cell line: Seems to bear part of the HeLa genomic sequence; may be a derivative of HeLa and another cell of unknown origin (PubMed=24991015).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00496.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Transcriptome analysis by RNAseq.
Misspelling: HOME-1; Note=Occasionally.
Disease Nasopharyngeal carcinoma (NCIt: C3871)
Nasopharyngeal carcinoma (ORDO: Orphanet_150)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_M595 (HONE-1/CPT30)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): PubMed=25877200

Markers:
AmelogeninX
CSF1PO10,11
D3S135815,18
D5S81811,12
D7S82010,12
D8S117912
D13S31710,12
D16S5399,10,11
D18S5113,16
D21S1127,30
FGA18,21
Penta D9,12
Penta E17,20
TH016,9
TPOX8,12
vWA14,16

Run an STR similarity search on this cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=2556716; DOI=10.1073/pnas.86.23.9524; PMCID=PMC298529
Glaser R., Zhang H.-Y., Yao K.-T., Zhu H.-C., Wang F.-X., Li G.-Y., Wen D.-S., Li Y.-P.
Two epithelial tumor cell lines (HNE-1 and HONE-1) latently infected with Epstein-Barr virus that were derived from nasopharyngeal carcinomas.
Proc. Natl. Acad. Sci. U.S.A. 86:9524-9528(1989)

PubMed=12097280
Chang J.-Y., Liu J.-F., Juang S.-H., Liu T.-W., Chen L.-T.
Novel mutation of topoisomerase I in rendering cells resistant to camptothecin.
Cancer Res. 62:3716-3721(2002)

PubMed=24991015; DOI=10.1128/JVI.01457-14; PMCID=PMC4178894
Strong M.J., Baddoo M., Nanbo A., Xu M., Puetter A., Lin Z.
Comprehensive high-throughput RNA sequencing analysis reveals contamination of multiple nasopharyngeal carcinoma cell lines with HeLa cell genomes.
J. Virol. 88:10696-10704(2014)

PubMed=25877200; DOI=10.1038/nature14397
Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M., Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S., Neve R.M.
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

CLPUB00484
Xu Z.-H., Sun W.-W., Hang J.-B., Gao B.-L., Hu J.-A.
RNA-seq identified a novel functional MET fusion in head and neck cancer 5-8F cell line.
Int. J. Clin. Exp. Pathol. 9:8308-8317(2016)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8706
TOKU-E; 3587
Anatomy/cell type resources BTO; BTO_0006136
Biological sample resources BioSample; SAMN03472391
Chemistry resources ChEMBL-Cells; CHEMBL3308670
ChEMBL-Targets; CHEMBL614830
PubChem_Cell_line; CVCL_8706
Encyclopedic resources Wikidata; Q54890147
Gene expression databases GEO; GSM375844
GEO; GSM378801
GEO; GSM378802
Polymorphism and mutation databases Cosmic; 755506
Cosmic; 944908
Cosmic; 1017620
Cosmic; 1300998
Cosmic; 1322948
Cosmic; 2366881
Progenetix; CVCL_8706
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number28