Cellosaurus cell line OU-AML-8 (CVCL

Cellosaurus OU-AML-8 (CVCL_8398)

Cross-references
Cell line name	OU-AML-8
Accession	CVCL_8398
Resource Identification Initiative	To cite this cell line use: OU-AML-8 (RRID:CVCL_8398)
Comments	Problematic cell line: Contaminated. Shown to be a OCI-AML-2 derivative (PubMed=12592342; PubMed=20143388). Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00254. Population: Caucasian. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations	Gene fusion; HGNC; 7137; AFDN + HGNC; 7132; KMT2A; Name(s)=KMT2A-AFDN, MLL-MLLT4, MLL-AF6 (from parent cell line).
Disease	Adult acute myeloid leukemia (NCIt: C9154) Acute myeloid leukemia with t(6;11)(q27;q23) KMT2A-MLLT4 (NCIt: C132105) Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_1619 (OCI-AML-2)
Sex of cell	Male
Age at sampling	65Y
Category	Cancer cell line
Web pages	https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications	PubMed=10027306; DOI=10.1038/sj.bjc.6690064; PMCID=PMC2362446 Zheng A.-P., Castren K., Saily M., Savolainen E.-R., Koistinen P.O., Vahakangas K.H. p53 status of newly established acute myeloid leukaemia cell lines. Br. J. Cancer 79:407-415(1999) PubMed=12592342; DOI=10.1038/sj.leu.2402799 Drexler H.G., Dirks W.G., Matsuo Y., MacLeod R.A.F. False leukemia-lymphoma cell lines: an update on over 500 cell lines. Leukemia 17:416-426(2003) PubMed=20143388; DOI=10.1002/ijc.25242 Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I. Check your cultures! A list of cross-contaminated or misidentified cell lines. Int. J. Cancer 127:1-8(2010)
Biological sample resources	BioSample; SAMN03151874
Encyclopedic resources	Wikidata; Q54936748
Entry history
Entry creation	04-Apr-2012
Last entry update	02-May-2024
Version number	25