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Cellosaurus HuL-1 (CVCL_8357)

[Text version]
Cell line name HuL-1
Synonyms HUL-1; Human Liver-1
Accession CVCL_8357
Resource Identification Initiative To cite this cell line use: HuL-1 (RRID:CVCL_8357)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=20143388). Originally thought to originate from a 4 month old male fetal liver.
Part of: JFCR45 cancer cell line panel.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00318.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
CVCL_WH70 (HuL-1.P3)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): JCRB; RCB


Run an STR similarity search on this cell line
Web pages https://cellbank.nibiohn.go.jp/legacy/cellbank/qualitycontrol/identification/summary.htm

Katsuta H., Takaoka T., Huh N.-H.
Establishment of tissue culture cell strains from normal fetal human liver and kidney.
Jpn. J. Exp. Med. 50:329-337(1980)

Manaka K.-i., Nonaka N., Yamada T., Hirai H.
Monoclonal antibodies against large-cell carcinoma of the lung.
Dokkyo J. Med. Sci. 12:31-41(1985)

PubMed=3986962; DOI=10.1093/carcin/6.4.549
Watatani M., Ikenaga M., Hatanaka T., Kinuta M., Takai S.-i., Mori T., Kondo S.
Analysis of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced DNA damage in tumor cell strains from Japanese patients and demonstration of MNNG hypersensitivity of Mer xenografts in athymic nude mice.
Carcinogenesis 6:549-553(1985)

PubMed=2836073; DOI=10.1247/csf.13.1
Sorimachi K., Hayashi T., Takaoka T., Niwa A., Yasumura Y.
Requirement of serum pretreatment for induction of alkaline phosphatase activity with prednisolone, butyrate, dibutyryl cyclic adenosine monophosphate and NaCl in human liver cells continuously cultured in serum-free medium.
Cell Struct. Funct. 13:1-11(1988)

PubMed=15767549; DOI=10.1158/1535-7163.MCT-04-0234
Nakatsu N., Yoshida Y., Yamazaki K., Nakamura T., Dan S., Fukui Y., Yamori T.
Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays.
Mol. Cancer Ther. 4:399-412(2005)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cell line collections (Providers) JCRB; NIHS0231 - Discontinued
RCB; RCB0077 - Discontinued
RCB; RCB1457 - Discontinued
Biological sample resources BioSample; SAMN03151718
BioSample; SAMN03472367
Encyclopedic resources Wikidata; Q54896866
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number27