Cell line name |
Hu609T |
Synonyms |
Hu 609T; HU 609 T |
Accession |
CVCL_8241 |
Resource Identification Initiative |
To cite this cell line use: Hu609T (RRID:CVCL_8241) |
Comments |
Problematic cell line: Contaminated. Parent cell line (Hu609) has been shown to be a J82 derivative. Population: Caucasian; Swedish. Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255. |
Sequence variations |
- Mutation; HGNC; 583; APC; Simple; p.Ser770Pro (c.2308T>C); ClinVar=VCV000140988; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 8975; PIK3CA; Simple; p.Pro124Leu (c.371C>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 9588; PTEN; Simple; p.Asn212fs*1 (c.635_1212del578); Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 9884; RB1; Simple; c.2107-2A>G; ClinVar=VCV000013077; Zygosity=Homozygous; Note=Splice acceptor mutation (from parent cell line).
- Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Glu271Lys (c.811G>A); ClinVar=VCV000406566; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Lys320Asn (c.960G>C); Zygosity=Heterozygous (from parent cell line).
|
Disease |
Bladder carcinoma (NCIt: C4912) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_8240 (Hu609) |
Sex of cell |
Male |
Age at sampling |
58Y |
Category |
Cancer cell line |
Publications | PubMed=7262169; DOI=10.1016/0014-2964(81)90123-7 Vilien M., Wolf H., Rasmussen F. Immunological characterization of cell lines establishing from malignant and normal human urothelium. Eur. J. Cancer 17:321-327(1981) PubMed=6546195; DOI=10.1007/BF00121494 Schroyens W., Mareel M.M., Dragonetti C.H. In vitro invasiveness of human bladder cancer from cell lines and biopsy specimens. Clin. Exp. Metastasis 1:153-162(1983) PubMed=8105864; DOI=10.1038/bjc.1993.449; PMCID=PMC1968741 Christensen B., Hansen C., Debiec-Rychter M., Kieler J., Ottensen S., Schmidt J. Identity of tumorigenic human urothelial cell lines and 'spontaneously' transformed sublines. Br. J. Cancer 68:879-884(1993) PubMed=8900435; DOI=10.1002/(SICI)1097-0215(19961009)68:2<239::AID-IJC17>3.0.CO;2-5 Klopocki A.G., Krop-Watorek A., Dus D., Ugorski M. Adhesion of human uroepithelial cells to E-selectin: possible involvement of sialosyl LewisA-ganglioside. Int. J. Cancer 68:239-244(1996) |
Cross-references |
Cell line databases/resources |
cancercelllines; CVCL_8241
|
Encyclopedic resources |
Wikidata; Q54896704
|
Entry history |
Entry creation | 04-Apr-2012 |
Last entry update | 05-Oct-2023 |
Version number | 19 |
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