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Cellosaurus HB11;19 (CVCL_8227)

[Text version]
Cell line name HB11;19
Synonyms HB(11;19); HB11.19; HB 11;19; HB1119
Accession CVCL_8227
Resource Identification Initiative To cite this cell line use: HB11;19 (RRID:CVCL_8227)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
From: Hing S.; Institute of Cancer Research; London; United Kingdom.
Omics: Array-based CGH.
Omics: Deep exome analysis.
Sequence variations
  • Mutation; HGNC; 1787; CDKN2A; Simple; p.Arg80Ter (c.237_238CC>TT) (c.237_238delinsTT) (p.Pro94Leu, c.280_281CC>TT); Zygosity=Homozygous (DepMap).
  • Mutation; HGNC; 11998; TP53; Simple; p.Thr125Met (c.374C>T); ClinVar=VCV000183748; Zygosity=Unspecified (DepMap).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Unspecified (DepMap).
Disease B acute lymphoblastic leukemia (NCIt: C8644)
Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=16523483; DOI=10.1002/gcc.20317
Horsley S.W., Mackay A., Iravani M., Fenwick K., Valgeirsson H., Dexter T.J., Ashworth A., Kearney L.
Array CGH of fusion gene-positive leukemia-derived cell lines reveals cryptic regions of genomic gain and loss.
Genes Chromosomes Cancer 45:554-564(2006)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8227
Cell_Model_Passport; SIDM01428
DepMap; ACH-001736
Encyclopedic resources Wikidata; Q54881357
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number17