ID   HB11;19
AC   CVCL_8227
SY   HB(11;19); HB11.19; HB 11;19; HB1119
DR   cancercelllines; CVCL_8227
DR   Cell_Model_Passport; SIDM01428
DR   DepMap; ACH-001736
DR   Wikidata; Q54881357
RX   PubMed=16523483;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   From: Hing S.; Institute of Cancer Research; London; United Kingdom.
CC   Sequence variation: Mutation; HGNC; 1787; CDKN2A; Simple; p.Arg80Ter (c.237_238CC>TT) (c.237_238delinsTT) (p.Pro94Leu, c.280_281CC>TT); Zygosity=Homozygous (DepMap=ACH-001736).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Thr125Met (c.374C>T); ClinVar=VCV000183748; Zygosity=Unspecified (DepMap=ACH-001736).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Unspecified (DepMap=ACH-001736).
CC   Omics: Array-based CGH.
CC   Omics: Deep exome analysis.
DI   NCIt; C8644; B acute lymphoblastic leukemia
DI   ORDO; Orphanet_99860; Precursor B-cell acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 18
//
RX   PubMed=16523483; DOI=10.1002/gcc.20317;
RA   Horsley S.W., Mackay A., Iravani M., Fenwick K., Valgeirsson H.,
RA   Dexter T.J., Ashworth A., Kearney L.;
RT   "Array CGH of fusion gene-positive leukemia-derived cell lines reveals
RT   cryptic regions of genomic gain and loss.";
RL   Genes Chromosomes Cancer 45:554-564(2006).
//