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Cellosaurus UT-SCC-8 (CVCL_7869)

[Text version]
Cell line name UT-SCC-8
Synonyms UTSCC8; University of Turku-Squamous Cell Carcinoma-8
Accession CVCL_7869
Resource Identification Initiative To cite this cell line use: UT-SCC-8 (RRID:CVCL_7869)
Comments Omics: Array-based CGH.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Larynx, supraglottis; UBERON=UBERON_0036263.
Sequence variations
Disease Laryngeal squamous cell carcinoma (NCIt: C4044)
Squamous cell carcinoma of the larynx (ORDO: Orphanet_494550)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 42Y
Category Cancer cell line
STR profile Source(s): PubMed=33802339

Markers:
AmelogeninX
CSF1PO10,11
D2S133819,25
D3S135815
D5S81810,11
D7S82010
D8S117913,14
D13S3178,14
D16S53912
D18S5113
D19S43313
D21S1130,31.2
FGA21
TH019.3
TPOX8
vWA14,16

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Publications

PubMed=8782485; DOI=10.1046/j.1365-2184.1996.01009.x
Servomaa K., Kiuru A., Grenman R., Pekkola-Heino K., Pulkkinen J.O., Rytomaa T.
p53 mutations associated with increased sensitivity to ionizing radiation in human head and neck cancer cell lines.
Cell Prolif. 29:219-230(1996)

PubMed=16715129; DOI=10.1038/sj.onc.1209690
Jarvinen A.-K., Autio R., Haapa-Paananen S., Wolf M., Saarela M., Grenman R., Leivo I., Kallioniemi O.-P., Makitie A.A., Monni O.
Identification of target genes in laryngeal squamous cell carcinoma by high-resolution copy number and gene expression microarray analyses.
Oncogene 25:6997-7008(2006)

PubMed=17312569; DOI=10.1002/hed.20478
Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L., Koch W.M., Ferris R.L., Lai S.Y.
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=29970484; DOI=10.1158/1535-7163.MCT-17-0733
Lepikhova T., Karhemo P.-R., Louhimo R., Yadav B., Murumagi A., Kulesskiy E., Kivento M., Sihto H., Grenman R., Syrjanen S.M., Kallioniemi O.-P., Aittokallio T., Wennerberg K., Joensuu H., Monni O.
Drug-sensitivity screening and genomic characterization of 45 HPV-negative head and neck carcinoma cell lines for novel biomarkers of drug efficacy.
Mol. Cancer Ther. 17:2060-2071(2018)

PubMed=33802339; DOI=10.3390/cancers13051069; PMCID=PMC7959143
Gottgens E.-L., Ansems M., Leenders W.P.J., Bussink J., Span P.N.
Genotyping and characterization of HPV status, hypoxia, and radiosensitivity in 22 head and neck cancer cell lines.
Cancers (Basel) 13:1069.1-1069.12(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_7869
Encyclopedic resources Wikidata; Q54992191
Gene expression databases GEO; GSM2883356
GEO; GSM2888819
Polymorphism and mutation databases IARC_TP53; 11065
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number16