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Cellosaurus UT-SCC-15 (CVCL_7811)

[Text version]
Cell line name UT-SCC-15
Synonyms UT-SCC 15; UTSCC15; University of Turku-Squamous Cell Carcinoma-15
Accession CVCL_7811
Resource Identification Initiative To cite this cell line use: UT-SCC-15 (RRID:CVCL_7811)
Comments Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Sequence variations
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line
STR profile Source(s): PubMed=33802339

Markers:
AmelogeninX
CSF1PO12,15
D2S133819
D3S135815
D5S81812,13
D7S8208,9
D8S117913
D13S31711
D16S53911,12
D18S5112,14
D19S43315,15.2
D21S1128
FGA25
TH016,8
TPOX8,9
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=8725545; DOI=10.3109/00016489609137854
Pekkola-Heino K., Servomaa K., Kiuru A., Grenman R.
Increased radiosensitivity is associated with p53 mutations in cell lines derived from oral cavity carcinoma.
Acta Oto-Laryngol. 116:341-344(1996)

PubMed=11799138; DOI=10.1177/002215540205000207
Eicheler W., Zips D., Dorfler A., Grenman R., Baumann M.
Splicing mutations in TP53 in human squamous cell carcinoma lines influence immunohistochemical detection.
J. Histochem. Cytochem. 50:197-204(2002)

PubMed=17312569; DOI=10.1002/hed.20478
Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L., Koch W.M., Ferris R.L., Lai S.Y.
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=18487078; DOI=10.1016/j.oraloncology.2008.02.006
Hoffmann T.K., Sonkoly E., Hauser U., van Lierop A., Whiteside T.L., Klussmann J.P., Hafner D., Schuler P.J., Friebe-Hoffmann U., Scheckenbach K., Erjala K., Grenman R., Schipper J., Bier H., Balz V.
Alterations in the p53 pathway and their association with radio- and chemosensitivity in head and neck squamous cell carcinoma.
Oral Oncol. 44:1100-1109(2008)

PubMed=20429727; DOI=10.3109/02841861003614343
Sorensen B.S., Toustrup K., Horsman M.R., Overgaard J., Alsner J.
Identifying pH independent hypoxia induced genes in human squamous cell carcinomas in vitro.
Acta Oncol. 49:895-905(2010)

PubMed=33802339; DOI=10.3390/cancers13051069; PMCID=PMC7959143
Gottgens E.-L., Ansems M., Leenders W.P.J., Bussink J., Span P.N.
Genotyping and characterization of HPV status, hypoxia, and radiosensitivity in 22 head and neck cancer cell lines.
Cancers (Basel) 13:1069.1-1069.12(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_7811
Anatomy/cell type resources BTO; BTO_0004441
Encyclopedic resources Wikidata; Q54992070
Gene expression databases GEO; GSM901099
GEO; GSM1716439
GEO; GSM1716440
GEO; GSM1716441
GEO; GSM1716442
Polymorphism and mutation databases Progenetix; CVCL_7811
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number17