ID   UT-SCC-15
AC   CVCL_7811
SY   UT-SCC 15; UTSCC15; University of Turku-Squamous Cell Carcinoma-15
DR   BTO; BTO_0004441
DR   cancercelllines; CVCL_7811
DR   GEO; GSM901099
DR   GEO; GSM1716439
DR   GEO; GSM1716440
DR   GEO; GSM1716441
DR   GEO; GSM1716442
DR   Progenetix; CVCL_7811
DR   Wikidata; Q54992070
RX   PubMed=8725545;
RX   PubMed=11799138;
RX   PubMed=17312569;
RX   PubMed=18487078;
RX   PubMed=20429727;
RX   PubMed=33802339;
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; c.560-1G>T; ClinVar=VCV003148249; Zygosity=Unspecified; Note=Splice acceptor mutation (PubMed=33802339).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
ST   Source(s): PubMed=33802339
ST   Amelogenin: X
ST   CSF1PO: 12,15
ST   D13S317: 11
ST   D16S539: 11,12
ST   D18S51: 12,14
ST   D19S433: 15,15.2
ST   D21S11: 28
ST   D2S1338: 19
ST   D3S1358: 15
ST   D5S818: 12,13
ST   D7S820: 8,9
ST   D8S1179: 13
ST   FGA: 25
ST   TH01: 6,8
ST   TPOX: 8,9
ST   vWA: 17,18
DI   NCIt; C4648; Tongue squamous cell carcinoma
DI   ORDO; Orphanet_457252; Squamous cell carcinoma of the oral tongue
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   51Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 17
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RX   PubMed=8725545; DOI=10.3109/00016489609137854;
RA   Pekkola-Heino K., Servomaa K., Kiuru A., Grenman R.;
RT   "Increased radiosensitivity is associated with p53 mutations in cell
RT   lines derived from oral cavity carcinoma.";
RL   Acta Oto-Laryngol. 116:341-344(1996).
//
RX   PubMed=11799138; DOI=10.1177/002215540205000207;
RA   Eicheler W., Zips D., Dorfler A., Grenman R., Baumann M.;
RT   "Splicing mutations in TP53 in human squamous cell carcinoma lines
RT   influence immunohistochemical detection.";
RL   J. Histochem. Cytochem. 50:197-204(2002).
//
RX   PubMed=17312569; DOI=10.1002/hed.20478;
RA   Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L.,
RA   Koch W.M., Ferris R.L., Lai S.Y.;
RT   "Head and neck squamous cell carcinoma cell lines: established models
RT   and rationale for selection.";
RL   Head Neck 29:163-188(2007).
//
RX   PubMed=18487078; DOI=10.1016/j.oraloncology.2008.02.006;
RA   Hoffmann T.K., Sonkoly E., Hauser U., van Lierop A., Whiteside T.L.,
RA   Klussmann J.P., Hafner D., Schuler P.J., Friebe-Hoffmann U.,
RA   Scheckenbach K., Erjala K., Grenman R., Schipper J., Bier H.,
RA   Balz V.;
RT   "Alterations in the p53 pathway and their association with radio- and
RT   chemosensitivity in head and neck squamous cell carcinoma.";
RL   Oral Oncol. 44:1100-1109(2008).
//
RX   PubMed=20429727; DOI=10.3109/02841861003614343;
RA   Sorensen B.S., Toustrup K., Horsman M.R., Overgaard J., Alsner J.;
RT   "Identifying pH independent hypoxia induced genes in human squamous
RT   cell carcinomas in vitro.";
RL   Acta Oncol. 49:895-905(2010).
//
RX   PubMed=33802339; DOI=10.3390/cancers13051069; PMCID=PMC7959143;
RA   Gottgens E.-L., Ansems M., Leenders W.P.J., Bussink J., Span P.N.;
RT   "Genotyping and characterization of HPV status, hypoxia, and
RT   radiosensitivity in 22 head and neck cancer cell lines.";
RL   Cancers (Basel) 13:1069.1-1069.12(2021).
//