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Cellosaurus UM-SCC-81B (CVCL_7784)

[Text version]
Cell line name UM-SCC-81B
Synonyms UMSCC-81B; UMSCC81B; University of Michigan-Squamous Cell Carcinoma-81B
Accession CVCL_7784
Resource Identification Initiative To cite this cell line use: UM-SCC-81B (RRID:CVCL_7784)
Comments Omics: CNV analysis.
Omics: Deep exome analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Oral cavity, tonsil, tonsillar pillar; UBERON=UBERON_0036274.
Sequence variations
Disease Tonsillar squamous cell carcinoma (NCIt: C8183)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_7783 ! UM-SCC-81A
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): PubMed=19760794

Markers:
AmelogeninX,Y
D3S135817
D5S81811,12
D7S8209,11
D8S117910,13
D13S3179,11
D18S5114
D21S1129
FGA20,22
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=9041179
Frank C.J., McClatchey K.D., Devaney K.O., Carey T.E.
Evidence that loss of chromosome 18q is associated with tumor progression.
Cancer Res. 57:824-827(1997)

PubMed=12884349; DOI=10.1002/hed.10274
Bradford C.R., Zhu S.-B., Ogawa H., Ogawa T., Ubell M., Narayan A., Johnson G., Wolf G.T., Fisher S.G., Carey T.E.
p53 mutation correlates with cisplatin sensitivity in head and neck squamous cell carcinoma lines.
Head Neck 25:654-661(2003)

PubMed=15287027; DOI=10.1002/gcc.20066
Takebayashi S., Hickson A., Ogawa T., Jung K.-Y., Mineta H., Ueda Y., Grenman R., Fisher S.G., Carey T.E.
Loss of chromosome arm 18q with tumor progression in head and neck squamous cancer.
Genes Chromosomes Cancer 41:145-154(2004)

PubMed=16785414; DOI=10.1001/archotol.132.6.668
Worsham M.J., Chen K.M., Meduri V., Nygren A.O.H., Errami A., Schouten J.P., Benninger M.S.
Epigenetic events of disease progression in head and neck squamous cell carcinoma.
Arch. Otolaryngol. Head Neck Surg. 132:668-677(2006)

PubMed=17312569; DOI=10.1002/hed.20478
Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L., Koch W.M., Ferris R.L., Lai S.Y.
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=19760794; DOI=10.1002/hed.21198; PMCID=PMC3292176
Brenner J.C., Graham M.P., Kumar B., Saunders L.M., Kupfer R., Lyons R.H., Bradford C.R., Carey T.E.
Genotyping of 73 UM-SCC head and neck squamous cell carcinoma cell lines.
Head Neck 32:417-426(2010)

PubMed=31090975; DOI=10.1002/hed.25803; PMCID=PMC6692232
Mann J.E., Kulkarni A., Birkeland A.C., Kafelghazal J., Eisenberg J., Jewell B.M., Ludwig M.L., Spector M.E., Jiang H., Carey T.E., Brenner J.C.
The molecular landscape of the University of Michigan laryngeal squamous cell carcinoma cell line panel.
Head Neck 41:3114-3124(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_7784
Encyclopedic resources Wikidata; Q54990931
Gene expression databases GEO; GSM3631285
Polymorphism and mutation databases IARC_TP53; 18886
Progenetix; CVCL_7784
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number20