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Cellosaurus UM-SCC-81A (CVCL_7783)

[Text version]
Cell line name UM-SCC-81A
Synonyms UMSCC-81A; UMSCC81A; University of Michigan-Squamous Cell Carcinoma-81A
Accession CVCL_7783
Resource Identification Initiative To cite this cell line use: UM-SCC-81A (RRID:CVCL_7783)
Comments Part of: MD Anderson Cell Lines Project.
Omics: CNV analysis.
Omics: Deep exome analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Larynx; UBERON=UBERON_0001737.
Sequence variations
  • Mutation; HGNC; 11998; TP53; None_reported; -; Zygosity=- (PubMed=12884349).
Disease Laryngeal squamous cell carcinoma (NCIt: C4044)
Squamous cell carcinoma of the larynx (ORDO: Orphanet_494550)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_7784 ! UM-SCC-81B
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
STR profile Source(s): PubMed=19760794

Markers:
AmelogeninX
D3S135815,17
D5S81811,12
D7S8209,11
D8S117910
D13S3179
D18S5114,19
D21S1133.2
FGA22
vWA17

Run an STR similarity search on this cell line
Web pages https://tcpaportal.org/mclp/
Publications

PubMed=9041179
Frank C.J., McClatchey K.D., Devaney K.O., Carey T.E.
Evidence that loss of chromosome 18q is associated with tumor progression.
Cancer Res. 57:824-827(1997)

PubMed=12884349; DOI=10.1002/hed.10274
Bradford C.R., Zhu S.-B., Ogawa H., Ogawa T., Ubell M., Narayan A., Johnson G., Wolf G.T., Fisher S.G., Carey T.E.
P53 mutation correlates with cisplatin sensitivity in head and neck squamous cell carcinoma lines.
Head Neck 25:654-661(2003)

PubMed=15287027; DOI=10.1002/gcc.20066
Takebayashi S., Hickson A., Ogawa T., Jung K.-Y., Mineta H., Ueda Y., Grenman R., Fisher S.G., Carey T.E.
Loss of chromosome arm 18q with tumor progression in head and neck squamous cancer.
Genes Chromosomes Cancer 41:145-154(2004)

PubMed=16785414; DOI=10.1001/archotol.132.6.668
Worsham M.J., Chen K.M., Meduri V., Nygren A.O.H., Errami A., Schouten J.P., Benninger M.S.
Epigenetic events of disease progression in head and neck squamous cell carcinoma.
Arch. Otolaryngol. Head Neck Surg. 132:668-677(2006)

PubMed=17312569; DOI=10.1002/hed.20478
Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L., Koch W.M., Ferris R.L., Lai S.Y.
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=19760794; DOI=10.1002/hed.21198
Brenner J.C., Graham M.P., Kumar B., Saunders L.M., Kupfer R., Lyons R.H., Bradford C.R., Carey T.E.
Genotyping of 73 UM-SCC head and neck squamous cell carcinoma cell lines.
Head Neck 32:417-426(2010)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

PubMed=31090975; DOI=10.1002/hed.25803
Mann J.E., Kulkarni A., Birkeland A.C., Kafelghazal J., Eisenberg J., Jewell B.M., Ludwig M.L., Spector M.E., Jiang H., Carey T.E., Brenner J.C.
The molecular landscape of the University of Michigan laryngeal squamous cell carcinoma cell line panel.
Head Neck 41:3114-3124(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_7783
Encyclopedic resources Wikidata; Q54990923
Gene expression databases GEO; GSM3631284
Polymorphism and mutation databases IARC_TP53; 21109
Progenetix; CVCL_7783
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number20