• Mutation; HGNC; HGNC:3595; FAT1; Simple; p.Met3586Thr (c.10757T>C); ClinVar=VCV000785111; Zygosity=Homozygous (PubMed=31541927).
  
• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys132Asn (c.396G>T); ClinVar=VCV000634773; Zygosity=Homozygous (PubMed=18006756; PubMed=23613873; PubMed=31541927).
  

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PubMed=1958593; DOI=10.1002/gcc.2870030406
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11p deletions and breakpoints in squamous cell carcinoma: association with altered reactivity with the UM-E7 antibody.
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DOI=10.1016/B978-0-12-333530-2.50007-1
Carey T.E.
Head and neck tumor cell lines.
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PubMed=8033114
Orr R.B., Kamen B.A.
UMSCC38 cells amplified at 11q13 for the folate receptor synthesize a mutant nonfunctional folate receptor.
Cancer Res. 54:3905-3911(1994)

PubMed=17312569; DOI=10.1002/hed.20478
Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L., Koch W.M., Ferris R.L., Lai S.Y.
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
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PubMed=18006756; DOI=10.1158/1078-0432.CCR-07-1591
Friedman J., Nottingham L.K., Duggal P., Pernas F.G., Yan B., Yang X.-P., Chen Z., Van Waes C.
Deficient TP53 expression, function, and cisplatin sensitivity are restored by quinacrine in head and neck cancer.
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PubMed=19760794; DOI=10.1002/hed.21198; PMCID=PMC3292176
Brenner J.C., Graham M.P., Kumar B., Saunders L.M., Kupfer R., Lyons R.H., Bradford C.R., Carey T.E.
Genotyping of 73 UM-SCC head and neck squamous cell carcinoma cell lines.
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PubMed=23613873; DOI=10.1371/journal.pone.0061555; PMCID=PMC3629194
Martens-de Kemp S.R., Dalm S.U., Wijnolts F.M.J., Brink A., Honeywell R.J., Peters G.J., Braakhuis B.J.M., Brakenhoff R.H.
DNA-bound platinum is the major determinant of cisplatin sensitivity in head and neck squamous carcinoma cells.
PLoS ONE 8:E61555-E61555(2013)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076
Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
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PubMed=31541927; DOI=10.1016/j.oraloncology.2019.09.004; PMCID=PMC7372097
van Harten A.M., Poell J.B., Buijze M., Brink A., Wells S.I., Leemans C.R., Wolthuis R.M.F., Brakenhoff R.H.
Characterization of a head and neck cancer-derived cell line panel confirms the distinct TP53-proficient copy number-silent subclass.
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PubMed=32574978; DOI=10.1016/j.tranon.2020.100808; PMCID=PMC7317296
Nair T.S., Thomas T.B., Yang L., Kakaraparthi B.N., Morris A.C., Clark A.M., Campredon L.P., Brouwer A.F., Eisenberg M.C., Meza R., Carey T.E.
Characteristics of head and neck squamous cell carcinoma cell lines reflect human tumor biology independent of primary etiologies and HPV status.
Transl. Oncol. 13:100808.1-100808.9(2020)