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Cellosaurus UM-SCC-27 (CVCL_7737)

[Text version]
Cell line name UM-SCC-27
Synonyms UMSCC-27; UMSCC27; University of Michigan-Squamous Cell Carcinoma-27
Accession CVCL_7737
Resource Identification Initiative To cite this cell line use: UM-SCC-27 (RRID:CVCL_7737)
Comments Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
STR profile Source(s): PubMed=19760794

Markers:
AmelogeninX,Y
D3S135814
D5S81812,13
D7S8208,11
D8S117912,13
D13S3178
D18S5114,16
D21S1129,32.2
FGA19
vWA17,18

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Publications

PubMed=16035614; DOI=10.1007/s10585-004-6918-5
Mandic R., Ludwig T., Oberleithner H., Werner J.A.
Evaluation of head and neck squamous cell carcinoma invasiveness by the electrical resistance breakdown assay.
Clin. Exp. Metastasis 21:699-704(2004)

PubMed=16203773; DOI=10.1158/1078-0432.CCR-05-0378
Mandic R., Schamberger C.J., Muller J.F., Geyer M., Zhu L., Carey T.E., Grenman R., Dunne A.A., Werner J.A.
Reduced cisplatin sensitivity of head and neck squamous cell carcinoma cell lines correlates with mutations affecting the COOH-terminal nuclear localization signal of p53.
Clin. Cancer Res. 11:6845-6852(2005)

PubMed=17312569; DOI=10.1002/hed.20478
Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L., Koch W.M., Ferris R.L., Lai S.Y.
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=19760794; DOI=10.1002/hed.21198; PMCID=PMC3292176
Brenner J.C., Graham M.P., Kumar B., Saunders L.M., Kupfer R., Lyons R.H., Bradford C.R., Carey T.E.
Genotyping of 73 UM-SCC head and neck squamous cell carcinoma cell lines.
Head Neck 32:417-426(2010)

Cross-references
Encyclopedic resources Wikidata; Q54990843
Polymorphism and mutation databases Cosmic; 1483460
IARC_TP53; 21638
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number17