ID   UM-SCC-27
AC   CVCL_7737
SY   UMSCC-27; UMSCC27; University of Michigan-Squamous Cell Carcinoma-27
DR   Cosmic; 1483460
DR   IARC_TP53; 21638
DR   Wikidata; Q54990843
RX   PubMed=16035614;
RX   PubMed=16203773;
RX   PubMed=17312569;
RX   PubMed=19760794;
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273Cys (c.817C>T); ClinVar=VCV000043594; Zygosity=Unspecified (PubMed=16203773).
CC   Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
ST   Source(s): PubMed=19760794
ST   Amelogenin: X,Y
ST   D13S317: 8
ST   D18S51: 14,16
ST   D21S11: 29,32.2
ST   D3S1358: 14
ST   D5S818: 12,13
ST   D7S820: 8,11
ST   D8S1179: 12,13
ST   FGA: 19
ST   vWA: 17,18
DI   NCIt; C4648; Tongue squamous cell carcinoma
DI   ORDO; Orphanet_457252; Squamous cell carcinoma of the oral tongue
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   62Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 17
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RX   PubMed=16035614; DOI=10.1007/s10585-004-6918-5;
RA   Mandic R., Ludwig T., Oberleithner H., Werner J.A.;
RT   "Evaluation of head and neck squamous cell carcinoma invasiveness by
RT   the electrical resistance breakdown assay.";
RL   Clin. Exp. Metastasis 21:699-704(2004).
//
RX   PubMed=16203773; DOI=10.1158/1078-0432.CCR-05-0378;
RA   Mandic R., Schamberger C.J., Muller J.F., Geyer M., Zhu L.,
RA   Carey T.E., Grenman R., Dunne A.A., Werner J.A.;
RT   "Reduced cisplatin sensitivity of head and neck squamous cell
RT   carcinoma cell lines correlates with mutations affecting the
RT   COOH-terminal nuclear localization signal of p53.";
RL   Clin. Cancer Res. 11:6845-6852(2005).
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RX   PubMed=17312569; DOI=10.1002/hed.20478;
RA   Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L.,
RA   Koch W.M., Ferris R.L., Lai S.Y.;
RT   "Head and neck squamous cell carcinoma cell lines: established models
RT   and rationale for selection.";
RL   Head Neck 29:163-188(2007).
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RX   PubMed=19760794; DOI=10.1002/hed.21198; PMCID=PMC3292176;
RA   Brenner J.C., Graham M.P., Kumar B., Saunders L.M., Kupfer R.,
RA   Lyons R.H., Bradford C.R., Carey T.E.;
RT   "Genotyping of 73 UM-SCC head and neck squamous cell carcinoma cell
RT   lines.";
RL   Head Neck 32:417-426(2010).
//