• Mutation; HGNC; HGNC:3595; FAT1; Simple; p.Ile1829Val (c.5485A>G); Zygosity=Homozygous (PubMed=31541927).
  
• Mutation; HGNC; HGNC:7881; NOTCH1; Simple; p.Ala12Val (c.35C>T); ClinVar=VCV001494610; Zygosity=Homozygous (PubMed=31541927).
  

PubMed=22162267; DOI=10.1002/hed.21962; PMCID=PMC3369005
Tang A.L., Hauff S.J., Owen J.H., Graham M.P., Czerwinski M.J., Park J.J., Walline H.M., Papagerakis S., Stoerker J., McHugh J.B., Chepeha D.B., Bradford C.R., Carey T.E., Prince M.E.P.
UM-SCC-104: a new human papillomavirus-16-positive cancer stem cell-containing head and neck squamous cell carcinoma cell line.
Head Neck 34:1480-1491(2012)

PubMed=24201445; DOI=10.1101/gr.164806.113; PMCID=PMC3912410
Akagi K., Li J.-F., Broutian T.R., Padilla-Nash H.M., Xiao W.-H., Jiang B., Rocco J.W., Teknos T.N., Kumar B., Wangsa D., He D., Ried T., Symer D.E., Gillison M.L.
Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability.
Genome Res. 24:185-199(2014)

PubMed=26045983; PMCID=PMC4449432
Ziemann F., Arenz A., Preising S., Wittekindt C., Klussmann J.P., Engenhart-Cabillic R., Wittig A.
Increased sensitivity of HPV-positive head and neck cancer cell lines to X-irradiation +/- cisplatin due to decreased expression of E6 and E7 oncoproteins and enhanced apoptosis.
Am. J. Cancer Res. 5:1017-1031(2015)

PubMed=28236344; DOI=10.1002/hed.24729; PMCID=PMC5392184
Walline H.M., Goudsmit C.M., McHugh J.B., Tang A.L., Owen J.H., Teh B.T., McKean E.L., Glover T.W., Graham M.P., Prince M.E.P., Chepeha D.B., Chinn S.B., Ferris R.L., Gollin S.M., Hoffmann T.K., Bier H., Brakenhoff R.H., Bradford C.R., Carey T.E.
University of Michigan Head and Neck Specialized Program of Research Excellence (SPORE) Program
Integration of high-risk human papillomavirus into cellular cancer-related genes in head and neck cancer cell lines.
Head Neck 39:840-852(2017)

PubMed=29156801; DOI=10.18632/oncotarget.21174; PMCID=PMC5689691
Kalu N.N., Mazumdar T., Peng S.-H., Shen L., Sambandam V., Rao X.-Y., Xi Y.-X., Li L.-R., Qi Y., Gleber-Netto F.O., Patel A., Wang J., Frederick M.J., Myers J.N., Pickering C.R., Johnson F.M.
Genomic characterization of human papillomavirus-positive and -negative human squamous cell cancer cell lines.
Oncotarget 8:86369-86383(2017)

PubMed=31541927; DOI=10.1016/j.oraloncology.2019.09.004; PMCID=PMC7372097
van Harten A.M., Poell J.B., Buijze M., Brink A., Wells S.I., Leemans C.R., Wolthuis R.M.F., Brakenhoff R.H.
Characterization of a head and neck cancer-derived cell line panel confirms the distinct TP53-proficient copy number-silent subclass.
Oral Oncol. 98:53-61(2019)

PubMed=32574978; DOI=10.1016/j.tranon.2020.100808; PMCID=PMC7317296
Nair T.S., Thomas T.B., Yang L., Kakaraparthi B.N., Morris A.C., Clark A.M., Campredon L.P., Brouwer A.F., Eisenberg M.C., Meza R., Carey T.E.
Characteristics of head and neck squamous cell carcinoma cell lines reflect human tumor biology independent of primary etiologies and HPV status.
Transl. Oncol. 13:100808.1-100808.9(2020)