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Cellosaurus U-1285dox (CVCL_7154)

[Text version]
Cell line name U-1285dox
Synonyms U-1285dox(900)
Accession CVCL_7154
Resource Identification Initiative To cite this cell line use: U-1285dox (RRID:CVCL_7154)
Comments Selected for resistance to: ChEBI; CHEBI_28748; Doxorubicin (Adriablastin; Adriamycin).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; c.376-1G>A (p.Tyr126_Lys132del, c.376_396del21); ClinVar=VCV000481003; Zygosity=Unspecified; Note=Splice acceptor mutation (from parent cell line).
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7153 (U-1285)
Sex of cell Male
Age at sampling 61Y
Category Cancer cell line
Publications

PubMed=12766562; DOI=10.1097/00007691-200306000-00014
Jonsson-Videsater K., Andersson G., Bergh J., Paul C.
Doxorubicin-resistant, MRP1-expressing U-1285 cells are sensitive to idarubicin.
Ther. Drug Monit. 25:331-339(2003)

Cross-references
Cell line databases/resources cancercelllines; CVCL_7154
Anatomy/cell type resources BTO; BTO_0002391
Encyclopedic resources Wikidata; Q54973512
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number16