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Cellosaurus U-1285 (CVCL_7153)

[Text version]
Cell line name U-1285
Synonyms U1285; 1285
Accession CVCL_7153
Resource Identification Initiative To cite this cell line use: U-1285 (RRID:CVCL_7153)
Comments Doubling time: 80-84 hours (PubMed=6285665).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; c.376-1G>A (p.Tyr126_Lys132del, c.376_396del21); ClinVar=VCV000481003; Zygosity=Unspecified; Note=Splice acceptor mutation (PubMed=12820372).
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_7154 (U-1285dox)
Sex of cell Male
Age at sampling 61Y
Category Cancer cell line
Publications

PubMed=6285665; DOI=10.1111/j.1699-0463.1982.tb00076_90A.x
Bergh J., Larsson E., Zech L., Nilsson K.
Establishment and characterization of two neoplastic cell lines (U-1285 and U-1568) derived from small cell carcinoma of the lung.
Acta Pathol. Microbiol. Immunol. Scand. A. 90:149-158(1982)

PubMed=2983887
Saksela K.M., Bergh J., Lehto V.-P., Nilsson K., Alitalo K.
Amplification of the c-myc oncogene in a subpopulation of human small cell lung cancer.
Cancer Res. 45:1823-1827(1985)

PubMed=12820372
Bergqvist M., Brattstrom D., Gullbo J., Hesselius P., Brodin O., Wagenius G.
p53 status and its in vitro relationship to radiosensitivity and chemosensitivity in lung cancer.
Anticancer Res. 23:1207-1212(2003)

PubMed=21508355
Hedman M., Bergqvist M., Brattstrom D., Brodin O.
Fractionated irradiation of five human lung cancer cell lines and prediction of survival according to a radiobiology model.
Anticancer Res. 31:1125-1130(2011)

Cross-references
Cell line databases/resources cancercelllines; CVCL_7153
Anatomy/cell type resources BTO; BTO_0002389
Encyclopedic resources Wikidata; Q54973511
Polymorphism and mutation databases IARC_TP53; 18697
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number15