• Mutation; HGNC; HGNC:11998; TP53; Simple; c.627_632AAACAC>CCCACACGCA; Zygosity=Unspecified (PubMed=7727782).
  

CLPUB00111
Hayashi Y., Kawamura M., Kobayashi S., Moriwaki K., Kobayashi M., Bessho F., Hanada R., Yamamoto K., Mori T., Nakazawa S., Yaginuma Y., Honma Y., Hozumi M.
Establishment and characterization of cell lines derived from childhood leukemias.
Int. J. Hematol. 57 Suppl. 1:124-124(1993)

PubMed=8139288; DOI=10.1016/0145-2126(94)90118-x
Sato S., Honma Y., Hozumi M., Hayashi Y., Matsuo Y., Shibata K., Omura S., Hino K.-i., Tomoyasu S., Tsuruoka N.
Effects of herbimycin A and its derivatives on growth and differentiation of Ph1-positive acute lymphoid leukemia cell lines.
Leuk. Res. 18:221-228(1994)

PubMed=7727782; DOI=10.1182/blood.V85.9.2546.bloodjournal8592546
Kawamura M., Kikuchi A., Kobayashi S., Hanada R., Yamamoto K., Horibe K., Shikano T., Ueda K., Hayashi K., Sekiya T., Hayashi Y.
Mutations of the p53 and ras genes in childhood t(1;19)-acute lymphoblastic leukemia.
Blood 85:2546-2552(1995)

PubMed=10233379; DOI=10.1111/j.1365-2141.1999.01284.x
Xu F., Taki T., Yang H.W., Hanada R., Hongo T., Ohnishi H., Kobayashi M., Bessho F., Yanagisawa M., Hayashi Y.
Tandem duplication of the FLT3 gene is found in acute lymphoblastic leukaemia as well as acute myeloid leukaemia but not in myelodysplastic syndrome or juvenile chronic myelogenous leukaemia in children.
Br. J. Haematol. 105:155-162(1999)

PubMed=14504097; DOI=10.1182/blood-2003-02-0418
Taketani T., Taki T., Sugita K., Furuichi Y., Ishii E., Hanada R., Tsuchida M., Sugita K., Ida K., Hayashi Y.
FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy.
Blood 103:1085-1088(2004)

PubMed=29786757; DOI=10.1007/s12185-018-2474-7
Tomoyasu C., Imamura T., Tomii T., Yano M., Asai D., Goto H., Shimada A., Sanada M., Iwamoto S., Takita J., Minegishi M., Inukai T., Sugita K., Hosoi H.
Copy number abnormality of acute lymphoblastic leukemia cell lines based on their genetic subtypes.
Int. J. Hematol. 108:312-318(2018)