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Cellosaurus Nu61 (CVCL_7086)

[Text version]
Cell line name Nu61
Synonyms NU61; nu61; nu61-8-4000
Accession CVCL_7086
Resource Identification Initiative To cite this cell line use: Nu61 (RRID:CVCL_7086)
Comments Characteristics: Established after 8 serial cycles of passage of the parental cell line in athymic nude mice and in vivo irradiation.
Transformant: NCIt; C17262; X-Ray.
Derived from site: In situ; Oral cavity, tongue, anterior part; UBERON=UBERON_0010032.
Sequence variations
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu542Lys (c.1624G>A); ClinVar=VCV000031944; Zygosity=Unspecified (from parent cell line).
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7118 (SCC-61)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Web pages https://strap.nci.nih.gov/celline_detail.php?sample_id=80
Publications

PubMed=14755057; DOI=10.1073/pnas.0308102100; PMCID=PMC341831
Khodarev N.N., Beckett M.A., Labay E., Darga T., Roizman B., Weichselbaum R.R.
STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells.
Proc. Natl. Acad. Sci. U.S.A. 101:1714-1719(2004)

Cross-references
Encyclopedic resources Wikidata; Q54931151
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number15