Cellosaurus logo
expasy logo

Cellosaurus KP-MRT-YM (CVCL_7052)

[Text version]
Cell line name KP-MRT-YM
Synonyms Kyoto Pediatrics-Malignant Rhabdoid Tumor-YM
Accession CVCL_7052
Resource Identification Initiative To cite this cell line use: KP-MRT-YM (RRID:CVCL_7052)
Comments Population: Japanese.
Derived from site: In situ; Chest wall; UBERON=UBERON_0016435.
Sequence variations
  • Gene deletion; HGNC; 11103; SMARCB1; Zygosity=Homozygous (PubMed=15378398).
Disease Extrarenal rhabdoid tumor (NCIt: C6586)
Rhabdoid tumor (ORDO: Orphanet_69077)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 5M
Category Cancer cell line
Publications

PubMed=15378398; DOI=10.1007/s10038-004-0191-y
Misawa A., Hosoi H., Imoto I., Iehara T., Sugimoto T., Inazawa J.
Translocation (1;22)(p36;q11.2) with concurrent del(22)(q11.2) resulted in homozygous deletion of SNF5/INI1 in a newly established cell line derived from extrarenal rhabdoid tumor.
J. Hum. Genet. 49:586-589(2004)

PubMed=18281554; DOI=10.1158/1078-0432.CCR-07-1661
Katsumi Y., Kuwahara Y., Tamura S., Kikuchi K., Otabe O., Tsuchiya K., Iehara T., Kuroda H., Hosoi H., Sugimoto T.
Trastuzumab activates allogeneic or autologous antibody-dependent cellular cytotoxicity against malignant rhabdoid tumor cells and interleukin-2 augments the cytotoxicity.
Clin. Cancer Res. 14:1192-1199(2008)

PubMed=21871868; DOI=10.1016/j.bbrc.2011.08.047; PMCID=PMC3214763
Katsumi Y., Iehara T., Miyachi M., Yagyu S., Tsubai-Shimizu S., Kikuchi K., Tamura S., Kuwahara Y., Tsuchiya K., Kuroda H., Sugimoto T., Houghton P.J., Hosoi H.
Sensitivity of malignant rhabdoid tumor cell lines to PD 0332991 is inversely correlated with p16 expression.
Biochem. Biophys. Res. Commun. 413:62-68(2011)

CLPUB00599
Sugimoto T., Kuroda H., Kuwahara Y., Katsumi Y., Misawa A., Moritake H., Hosoi H.
Cellular and molecular characteristics of established childhood soft-tissue sarcoma cell lines.
J. Cancer Res. Therap. Oncol. 7:202.1-202.12(2019)

Cross-references
Encyclopedic resources Wikidata; Q54900384
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number13