ID   KP-MRT-YM
AC   CVCL_7052
SY   Kyoto Pediatrics-Malignant Rhabdoid Tumor-YM
DR   Wikidata; Q54900384
RX   CelloPub=CLPUB00599;
RX   PubMed=15378398;
RX   PubMed=18281554;
RX   PubMed=21871868;
CC   Population: Japanese.
CC   Sequence variation: Gene deletion; HGNC; 11103; SMARCB1; Zygosity=Homozygous (PubMed=15378398).
CC   Derived from site: In situ; Chest wall; UBERON=UBERON_0016435.
DI   NCIt; C6586; Extrarenal rhabdoid tumor
DI   ORDO; Orphanet_69077; Rhabdoid tumor
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   5M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 13
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RX   CelloPub=CLPUB00599;
RA   Sugimoto T., Kuroda H., Kuwahara Y., Katsumi Y., Misawa A.,
RA   Moritake H., Hosoi H.;
RT   "Cellular and molecular characteristics of established childhood
RT   soft-tissue sarcoma cell lines.";
RL   J. Cancer Res. Therap. Oncol. 7:202.1-202.12(2019).
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RX   PubMed=15378398; DOI=10.1007/s10038-004-0191-y;
RA   Misawa A., Hosoi H., Imoto I., Iehara T., Sugimoto T., Inazawa J.;
RT   "Translocation (1;22)(p36;q11.2) with concurrent del(22)(q11.2)
RT   resulted in homozygous deletion of SNF5/INI1 in a newly established
RT   cell line derived from extrarenal rhabdoid tumor.";
RL   J. Hum. Genet. 49:586-589(2004).
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RX   PubMed=18281554; DOI=10.1158/1078-0432.CCR-07-1661;
RA   Katsumi Y., Kuwahara Y., Tamura S., Kikuchi K., Otabe O., Tsuchiya K.,
RA   Iehara T., Kuroda H., Hosoi H., Sugimoto T.;
RT   "Trastuzumab activates allogeneic or autologous antibody-dependent
RT   cellular cytotoxicity against malignant rhabdoid tumor cells and
RT   interleukin-2 augments the cytotoxicity.";
RL   Clin. Cancer Res. 14:1192-1199(2008).
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RX   PubMed=21871868; DOI=10.1016/j.bbrc.2011.08.047; PMCID=PMC3214763;
RA   Katsumi Y., Iehara T., Miyachi M., Yagyu S., Tsubai-Shimizu S.,
RA   Kikuchi K., Tamura S., Kuwahara Y., Tsuchiya K., Kuroda H.,
RA   Sugimoto T., Houghton P.J., Hosoi H.;
RT   "Sensitivity of malignant rhabdoid tumor cell lines to PD 0332991 is
RT   inversely correlated with p16 expression.";
RL   Biochem. Biophys. Res. Commun. 413:62-68(2011).
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