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Cellosaurus HA22T/VGH (CVCL_7046)

[Text version]
Cell line name HA22T/VGH
Synonyms Ha22T/VGH; HA 22T/VGH; HA22T
Accession CVCL_7046
Resource Identification Initiative To cite this cell line use: HA22T/VGH (RRID:CVCL_7046)
Comments Population: Chinese.
Karyotypic information: Has lost chromosome Y.
Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).
Omics: Mitochondrial genome sequenced.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 1787; CDKN2A; Simple; p.Arg22Glyfs*14 (c.63_85del23); Zygosity=Unspecified (PubMed=7972006).
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 52Y
Category Cancer cell line
STR profile Source(s): BCRC=60168

Markers:
AmelogeninX,Y
CSF1PO11,12
D5S8187,12
D7S82011,12
D13S31712
D16S53911
TH017,9
TPOX9,11
vWA14,18

Run an STR similarity search on this cell line
Web pages http://www.abscience.com.tw/chinese/03product/01product_content.php?pid=2&tid=15&id=82
Publications

PubMed=6291875
Lin Y.-M., Hu C.-P., Chou C.-K., O-Lee T.-W., Wuu K.-D., Chen T.-Y., P'eng F.-K., Liu T.-J., Ko J.-L., Chang C.-M.
A new human hepatoma cell line: establishment and characterization.
Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi 15:193-201(1982)

PubMed=6683778; DOI=10.1128/mcb.3.6.1133-1137.1983; PMCID=PMC368642
Chang C.-M., Lin Y.-M., O-Lee T.-W., Chou C.-K., Lee T.-S., Liu T.-J., P'eng F.-K., Chen T.-Y., Hu C.-P.
Induction of plasma protein secretion in a newly established human hepatoma cell line.
Mol. Cell. Biol. 3:1133-1137(1983)

PubMed=3023526; DOI=10.1099/0022-1317-67-11-2315
Aspinall S., Alexander J.J., Bos P.
Comparative expression of hepatitis B virus antigens in several cell model systems.
J. Gen. Virol. 67:2315-2323(1986)

DOI=10.1007/978-4-431-68349-0_4
Alexander J.J.
Human hepatoma cell lines.
(In book chapter) Neoplasms of the liver; Okuda K., Ishak K.G. (eds.); pp.47-56; Springer; Tokyo; Japan (1987)

PubMed=2441881; DOI=10.1016/0309-1651(87)90081-6
Lo S.-C.J., Yang C.-W., Hu C.-P., Chang C.-M.
Absence of cytokeratin in human hepatoma cell lines.
Cell Biol. Int. Rep. 11:477-486(1987)

PubMed=3032404; DOI=10.1016/0165-4608(87)90062-8
Wuu K.-D., Kang L., Su Y.-M., Wuu S.-W., Hu C.-P., Chang C.-M.
Karyotypic characterization of an established human hepatoma cell line HA22T/VGH.
Cancer Genet. Cytogenet. 26:279-286(1987)

PubMed=8224613; DOI=10.1096/fasebj.7.14.8224613
Puisieux A., Galvin K., Troalen F., Bressac B., Marcais C., Galun E., Ponchel F., Yakicier C., Ji J.-W., Ozturk M.
Retinoblastoma and p53 tumor suppressor genes in human hepatoma cell lines.
FASEB J. 7:1407-1413(1993)

PubMed=7972006; DOI=10.1073/pnas.91.23.11045; PMCID=PMC45163
Okamoto A., Demetrick D.J., Spillare E.A., Hagiwara K., Hussain S.P., Bennett W.P., Forrester K., Gerwin B.I., Serrano M., Beach D.H., Harris C.C.
Mutations and altered expression of p16INK4 in human cancer.
Proc. Natl. Acad. Sci. U.S.A. 91:11045-11049(1994)

PubMed=8050184; DOI=10.1111/j.1365-2249.1994.tb06089.x; PMCID=PMC1534706
Wadee A.A., Paterson A., Coplan K.A., Reddy S.G.
HLA expression in hepatocellular carcinoma cell lines.
Clin. Exp. Immunol. 97:328-333(1994)

PubMed=29051253; DOI=10.1128/genomeA.01136-17; PMCID=PMC5646406
Huang D.-G., Cheng G., Wu J.-C.
Complete mitochondrial genome of the human liver cancer HA22T cell line.
Genome Announc. 5:e01136.17.1-e01136.17.2(2017)

Cross-references
Cell line collections (Providers) BCRC; 60168
Anatomy/cell type resources BTO; BTO:0002429
Chemistry resources ChEMBL-Cells; CHEMBL3308657
ChEMBL-Targets; CHEMBL614807
PubChem_Cell_line; CVCL_7046
Encyclopedic resources Wikidata; Q54872284
Polymorphism and mutation databases Cosmic; 932991
Cosmic; 934552
Cosmic; 2668280
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number23