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Cellosaurus HIOEC (CVCL_6E43)

[Text version]
Cell line name HIOEC
Synonyms Human Immortalized Oral Epithelial Cells
Accession CVCL_6E43
Resource Identification Initiative To cite this cell line use: HIOEC (RRID:CVCL_6E43)
Comments Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Oral cavity, oral mucosa; UBERON=UBERON_0003729.
Cell type: Epithelial cell; CL=CL_0000066.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C1LE (HIOEC-B(a)P-56)CVCL_6E44 (HIOEC-B(a)P-96)CVCL_C1LG (HIOEC-B(a)P-TPA)
Sex of cell Female
Age at sampling Age unspecified
Category Transformed cell line
Publications

Patent=CN1730663A
Zhang Z.-Z., Pan H.-Y., Cao J., Pa T.-M., Zhou X.-J., Chen W.-T., Li J., Zhang P., He R.-G.
A kind of oral mucosa epithelial cell canceration model.
Patent number CN1730663A, 08-Feb-2006

PubMed=16513324; DOI=10.1016/j.ijom.2006.01.017
Sdek P., Zhang Z.-Y., Cao J., Pan H.-Y., Chen W.-T., Zheng J.-W.
Alteration of cell-cycle regulatory proteins in human oral epithelial cells immortalized by HPV16 E6 and E7.
Int. J. Oral Maxillofac. Surg. 35:653-657(2006)

PubMed=16685356
Pan H.-Y., Zhang Z.-Y., Zhou X.-J., Li J., Zhang P., Chen W.-T.
The establishment of B(a)P and TPA transformed cell line and its biological characteristics.
Shanghai Kou Qiang Yi Xue 15:152-156(2006)

PubMed=18206853; DOI=10.1016/j.archoralbio.2007.12.002
Zhong L.-P., Pan H.-Y., Zhou X.-J., Ye D.-X., Zhang L., Yang X., Chen W.-T., Zhang Z.-Y.
Characteristics of a cancerous cell line, HIOEC-B(a)P-96, induced by benzo(a)pyrene from human immortalized oral epithelial cell line.
Arch. Oral Biol. 53:443-452(2008)

Cross-references
Encyclopedic resources Wikidata; Q54889587
Entry history
Entry creation23-Feb-2016
Last entry update10-Sep-2024
Version number12