ID   HIOEC
AC   CVCL_6E43
SY   Human Immortalized Oral Epithelial Cells
DR   Wikidata; Q54889587
RX   Patent=CN1730663A;
RX   PubMed=16513324;
RX   PubMed=16685356;
RX   PubMed=18206853;
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Derived from site: In situ; Oral cavity, oral mucosa; UBERON=UBERON_0003729.
CC   Cell type: Epithelial cell; CL=CL_0000066.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Age unspecified
CA   Transformed cell line
DT   Created: 23-02-16; Last updated: 10-09-24; Version: 12
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RX   Patent=CN1730663A;
RA   Zhang Z.-Z., Pan H.-Y., Cao J., Pa T.-M., Zhou X.-J., Chen W.-T., Li J.,
RA   Zhang P., He R.-G.;
RT   "A kind of oral mucosa epithelial cell canceration model.";
RL   Patent number CN1730663A, 08-Feb-2006.
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RX   PubMed=16513324; DOI=10.1016/j.ijom.2006.01.017;
RA   Sdek P., Zhang Z.-Y., Cao J., Pan H.-Y., Chen W.-T., Zheng J.-W.;
RT   "Alteration of cell-cycle regulatory proteins in human oral epithelial
RT   cells immortalized by HPV16 E6 and E7.";
RL   Int. J. Oral Maxillofac. Surg. 35:653-657(2006).
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RX   PubMed=16685356;
RA   Pan H.-Y., Zhang Z.-Y., Zhou X.-J., Li J., Zhang P., Chen W.-T.;
RT   "The establishment of B(a)P and TPA transformed cell line and its
RT   biological characteristics.";
RL   Shanghai Kou Qiang Yi Xue 15:152-156(2006).
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RX   PubMed=18206853; DOI=10.1016/j.archoralbio.2007.12.002;
RA   Zhong L.-P., Pan H.-Y., Zhou X.-J., Ye D.-X., Zhang L., Yang X.,
RA   Chen W.-T., Zhang Z.-Y.;
RT   "Characteristics of a cancerous cell line, HIOEC-B(a)P-96, induced by
RT   benzo(a)pyrene from human immortalized oral epithelial cell line.";
RL   Arch. Oral Biol. 53:443-452(2008).
//