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Cellosaurus WM1361B (CVCL_6993)

[Text version]
Cell line name WM1361B
Synonyms WM-1361B; WM 1361B
Accession CVCL_6993
Resource Identification Initiative To cite this cell line use: WM1361B (RRID:CVCL_6993)
Comments Part of: Wistar Institute melanoma cell line collection.
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Skin; UBERON=UBERON_0002097.
Sequence variations
  • Gene deletion; HGNC; HGNC:9588; PTEN; Zygosity=Hemizygous (from autologous cell line WM1361A).
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=16827748).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000013900; Zygosity=Homozygous (from autologous cell line WM1361A).
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_6788 ! WM1361A
CVCL_6994 ! WM1361C
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=2253310; DOI=10.1007/BF00046337
Herlyn M.
Human melanoma: development and progression.
Cancer Metastasis Rev. 9:101-112(1990)

PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x
Hoek K.S., Schlegel N.C., Brafford P., Sucker A., Ugurel S., Kumar R., Weber B.L., Nathanson K.L., Phillips D.J., Herlyn M., Schadendorf D., Dummer R.
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Pigment Cell Res. 19:290-302(2006)

PubMed=18632627; DOI=10.1158/0008-5472.CAN-08-0235; PMCID=PMC2615688
Smalley K.S.M., Contractor R., Nguyen T.K., Xiao M., Edwards R., Muthusamy V., King A.J., Flaherty K.T., Bosenberg M.W., Herlyn M., Nathanson K.L.
Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression.
Cancer Res. 68:5743-5752(2008)

Cross-references
Cell line databases/resources cancercelllines; CVCL_6993
Encyclopedic resources Wikidata; Q54994170
Gene expression databases GEO; GSM109026
Polymorphism and mutation databases Cosmic; 686403
Cosmic; 1155555
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number23