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Cellosaurus WM1361A (CVCL_6788)

[Text version]
Cell line name WM1361A
Synonyms WM-1361A; WM 1361A; WC00075; EST69
Accession CVCL_6788
Resource Identification Initiative To cite this cell line use: WM1361A (RRID:CVCL_6788)
Comments Part of: Wistar Institute melanoma cell line collection.
Omics: Array-based CGH.
Omics: Transcriptome analysis by microarray.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=17260012; Wistar).
  • Gene deletion; HGNC; 1788; CDKN2B; Zygosity=Homozygous (Wistar).
  • Gene deletion; HGNC; 9588; PTEN; Zygosity=Hemizygous (Wistar).
  • Mutation; HGNC; 1097; BRAF; None_reported; -; Zygosity=- (Wistar).
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000013900; Zygosity=Homozygous (PubMed=17260012; PubMed=23851445; Wistar).
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_6993 ! WM1361B
CVCL_6994 ! WM1361C
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): ESTDAB=ESTDAB-069; Wistar

Markers:
AmelogeninX,Y
CSF1PO10,11
D2S133825
D3S135816
D5S81811
D7S8208,10
D8S117912,13
D13S31711
D16S53911,12
D18S5114
D19S43313,14
D21S1130,31.2
FGA22,25
TH017 (Wistar)
7,8 (ESTDAB=ESTDAB-069)
TPOX8,11
vWA14,17

Run an STR similarity search on this cell line
Web pages https://www.wistar.org/our-scientists/meenhard-herlyn
Publications

PubMed=2253310; DOI=10.1007/BF00046337
Herlyn M.
Human melanoma: development and progression.
Cancer Metastasis Rev. 9:101-112(1990)

PubMed=2068080; DOI=10.1073/pnas.88.14.6028
Cornil I., Theodorescu D., Man S., Herlyn M., Jambrosic J.A., Kerbel R.S.
Fibroblast cell interactions with human melanoma cells affect tumor cell growth as a function of tumor progression.
Proc. Natl. Acad. Sci. U.S.A. 88:6028-6032(1991)

PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x
Hoek K.S., Schlegel N.C., Brafford P., Sucker A., Ugurel S., Kumar R., Weber B.L., Nathanson K.L., Phillips D.J., Herlyn M., Schadendorf D., Dummer R.
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Pigment Cell Res. 19:290-302(2006)

PubMed=17260012; DOI=10.1038/sj.onc.1210252
Jonsson G., Dahl C., Staaf J., Sandberg T., Bendahl P.-O., Ringner M., Guldberg P., Borg A.
Genomic profiling of malignant melanoma using tiling-resolution arrayCGH.
Oncogene 26:4738-4748(2007)

PubMed=18632627; DOI=10.1158/0008-5472.CAN-08-0235
Smalley K.S.M., Contractor R., Nguyen T.K., Xiao M., Edwards R., Muthusamy V., King A.J., Flaherty K.T., Bosenberg M.W., Herlyn M., Nathanson K.L.
Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression.
Cancer Res. 68:5743-5752(2008)

PubMed=19340423; DOI=10.1007/s00262-009-0701-z
Mendez R., Aptsiauri N., Del Campo A., Maleno I., Cabrera T., Ruiz-Cabello Osuna F., Garrido F., Garcia-Lora A.
HLA and melanoma: multiple alterations in HLA class I and II expression in human melanoma cell lines from ESTDAB cell bank.
Cancer Immunol. Immunother. 58:1507-1515(2009)

PubMed=23851445; DOI=10.1158/1541-7786.MCR-13-0006
Dahl C., Christensen C., Jonsson G., Lorentzen A., Skjodt M.L., Borg A., Pawelec G., Guldberg P.
Mutual exclusivity analysis of genetic and epigenetic drivers in melanoma identifies a link between p14 ARF and RARbeta signaling.
Mol. Cancer Res. 11:1166-1178(2013)

Cross-references
Cell line collections (Providers) Coriell; WC00075 - Discontinued
Rockland; WM1361A-01-0001
Cell line databases/resources cancercelllines; CVCL_6788
ESTDAB; ESTDAB-069
CRISP screens repositories BioGRID_ORCS_Cell_line; 1751
Encyclopedic resources Wikidata; Q54994168
Gene expression databases GEO; GSM109025
GEO; GSM156022
GEO; GSM185174
GEO; GSM185175
GEO; GSM185176
GEO; GSM185177
GEO; GSM952593
Polymorphism and mutation databases Cosmic; 686402
Cosmic; 1047649
Cosmic; 1155284
Cosmic; 1155540
Cosmic; 1303063
Cosmic; 1507599
Cosmic; 1669263
Cosmic; 2163799
Cosmic; 2233686
IARC_TP53; 26076
Progenetix; CVCL_6788
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number28