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Cellosaurus WM3248 (CVCL_6798)

[Text version]
Cell line name WM3248
Synonyms WM-3248; WM 3248; WC00081
Accession CVCL_6798
Resource Identification Initiative To cite this cell line use: WM3248 (RRID:CVCL_6798)
Comments Part of: Wistar Institute melanoma cell line collection.
Omics: Transcriptome analysis by microarray.
Misspelling: WM-3428; Cosmic=1303073.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (Wistar).
  • Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (Wistar).
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Homozygous (Wistar).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys144Ter (c.430A>T); ClinVar=VCV000379501; Zygosity=Homozygous (Wistar).
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Web pages https://www.wistar.org/our-scientists/meenhard-herlyn
Publications

PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x
Hoek K.S., Schlegel N.C., Brafford P., Sucker A., Ugurel S., Kumar R., Weber B.L., Nathanson K.L., Phillips D.J., Herlyn M., Schadendorf D., Dummer R.
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Pigment Cell Res. 19:290-302(2006)

PubMed=18632627; DOI=10.1158/0008-5472.CAN-08-0235; PMCID=PMC2615688
Smalley K.S.M., Contractor R., Nguyen T.K., Xiao M., Edwards R., Muthusamy V., King A.J., Flaherty K.T., Bosenberg M.W., Herlyn M., Nathanson K.L.
Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression.
Cancer Res. 68:5743-5752(2008)

Cross-references
Cell line collections (Providers) Coriell; WC00081 - Discontinued
Rockland; WM3248-01-0001
Cell line databases/resources cancercelllines; CVCL_6798
Encyclopedic resources Wikidata; Q54994244
Gene expression databases GEO; GSM109037
GEO; GSM185196
GEO; GSM185197
GEO; GSM188066
GEO; GSM188118
GEO; GSM188191
GEO; GSM188206
GEO; GSM188215
GEO; GSM188234
GEO; GSM188264
GEO; GSM188282
GEO; GSM188291
GEO; GSM188323
Polymorphism and mutation databases Cosmic; 1155546
Cosmic; 1303073
Progenetix; CVCL_6798
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number23