ID   WM3248
AC   CVCL_6798
SY   WM-3248; WM 3248; WC00081
DR   cancercelllines; CVCL_6798
DR   Coriell; WC00081
DR   Cosmic; 1155546
DR   Cosmic; 1303073
DR   GEO; GSM109037
DR   GEO; GSM185196
DR   GEO; GSM185197
DR   GEO; GSM188066
DR   GEO; GSM188118
DR   GEO; GSM188191
DR   GEO; GSM188206
DR   GEO; GSM188215
DR   GEO; GSM188234
DR   GEO; GSM188264
DR   GEO; GSM188282
DR   GEO; GSM188291
DR   GEO; GSM188323
DR   Progenetix; CVCL_6798
DR   Rockland; WM3248-01-0001
DR   Wikidata; Q54994244
RX   PubMed=16827748;
RX   PubMed=18632627;
WW   https://www.wistar.org/our-scientists/meenhard-herlyn
CC   Part of: Wistar Institute melanoma cell line collection.
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (Wistar).
CC   Sequence variation: Gene deletion; HGNC; 1788; CDKN2B; Zygosity=Homozygous (Wistar).
CC   Sequence variation: Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Homozygous (Wistar).
CC   Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; p.Lys144Ter (c.430A>T); ClinVar=VCV000379501; Zygosity=Homozygous (Wistar).
CC   Omics: Transcriptome analysis by microarray.
CC   Misspelling: WM-3428; Cosmic=1303073.
CC   Discontinued: Coriell; WC00081; probable.
DI   NCIt; C3510; Cutaneous melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 22
//
RX   PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x;
RA   Hoek K.S., Schlegel N.C., Brafford P., Sucker A., Ugurel S., Kumar R.,
RA   Weber B.L., Nathanson K.L., Phillips D.J., Herlyn M., Schadendorf D.,
RA   Dummer R.;
RT   "Metastatic potential of melanomas defined by specific gene expression
RT   profiles with no BRAF signature.";
RL   Pigment Cell Res. 19:290-302(2006).
//
RX   PubMed=18632627; DOI=10.1158/0008-5472.CAN-08-0235;
RA   Smalley K.S.M., Contractor R., Nguyen T.K., Xiao M., Edwards R.,
RA   Muthusamy V., King A.J., Flaherty K.T., Bosenberg M.W., Herlyn M.,
RA   Nathanson K.L.;
RT   "Identification of a novel subgroup of melanomas with
RT   KIT/cyclin-dependent kinase-4 overexpression.";
RL   Cancer Res. 68:5743-5752(2008).
//